Phenethyl Caffeate Phenethyl caffeate is a compound found in propolis, a mixture produced by bees. Phenethyl caffeate exhibits anti-inflammatory, anti-atherosclerotic, antioxidative, cardioprotective, anti-obesity, and anticancer chemotherapeutic activities. In vitro, phenethyl…
Phellodendrine Phellodendrine is a quaternary base alkaloid found in the bark of Phellodendron. Phellodendrine exhibits immunosuppressive and anti-inflammatory activities. Phellodendrine inhibits local semisyngenic and allogenic graft-versus-host (GVH) reactions and suppresses…
Phalloidin Phalloidin is a phallotoxin found in Amanita phalloides that exhibits cytotoxic activity. Phalloidin binds F-actin and inhibits depolymerization; it locks adjacent subunits together, preventing actin ATP hydrolysis. Fluorescent-tagged conjugates…
Phallacidin Phallicidin is a phallotoxin found in Amanita phalloides that exhibits cytotoxic activity. Phallicidin binds F-actin and inhibits depolymerization; it locks adjacent subunits together, preventing actin ATP hydrolysis. Fluorescent-tagged conjugates…
PFI-1 PFI-1 is an inhibitor of BET bromodomains (BRDs) that prevents the association of BET with histones; it acts as an acyl-lysine (Kac) mimetic inhibitor, binding the Kac site of…
PF-06447475 PF-06447475 inhibits leucine-rich repeat kinase 2 (LRRK2), exhibiting neuroprotective activity. In animal models of Parkinson’s disease, this compound suppresses neuroinflammation and neurodegeneration. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18953056 Cas No. 1527473-33-1 Formula…
PF-04217903 PF-04217903 is a triazolopyrazine inhibitor of c-MET that displays anticancer chemotherapeutic and anti-metastatic activities. PF-04217903 inhibits cell proliferation, invasion, and migration as well as tumor growth in various cancer…
Perifosine Perifosine is an alkylphospholipid analog that exhibits anticancer chemotherapeutic and anti-inflammatory activities. Perifosine directly inhibits Akt by binding at multiple sites. In macrophages, perifosine inhibits LPS-induced increases in TNF-α…
Peptide YY, pig Peptide YY is an endogenous neuropeptide Y-related peptide that activates Y1 and Y2 receptors. Peptide YY is an appetite-regulating hormone secreted from the gastrointestinal tract that exhibits…
Peptide YY, human Peptide YY is an endogenous neuropeptide Y-related peptide that activates Y1 and Y2 receptors. Peptide YY is an appetite-regulating hormone secreted from the gastrointestinal tract that exhibits…