Ac-YVAD-pNA This peptide is a substrate for caspase 1 and is used to measure caspase activity in cellular assays. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18835492 Purity ≥95% Formula C29H36N6O10 Formula Wt. 628.6 Solubility…
Ac-VEID-pNA Ac-VEID-pNA is a peptide substrate used to measure activity of caspase 6. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18835480 Purity ≥95% Formula C28H40N6O11 Formula Wt. 636.6 Solubility DMSO Kanazawa T, Kono T, Watanabe…
Ac-SDKP Ac-SKDP is a pro-angiogenic peptide degradation product of thymosin B4 that regulates hematopoiesis by inhibiting proliferation of hematopoietic pluripotent stem cells (spleen colony-forming units, or CFUs). This peptide exhibits…
Ac-LEHD-pNa Ac-LEHD-PNA is a synthetic peptide substrate for caspase 9 that is used in vitro to measure caspase 9 activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18835389 Purity ≥95% Formula C29H38N8O11 Formula Wt. 674.7…
Ac-IEAR-pNA Ac-IEAR-pNA is a peptide substrate used to measure activity of caspases. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18835247 Purity ≥95% Formula C28H43N9O9 Formula Wt. 649.7 Eliglustat
Ac-GPK(Ac)-pNA Ac-IEAR-pNA is a peptide substrate used to measure activity of caspases. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18835139 Purity ≥95% Formula C23H32N6O7 Formula Wt. 504.5 AVE 0991
Ac-D-E Ac-DE is a mast cell stabilizer that exhibits anti-allergic and antihistamine activity; it is clinically used to treat seasonal allergic rhinitis. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18835063 Cas No. 3106-85-2 Purity ≥95%…
ABT-737 ABT-737 is a BH3 mimetic that acts as an inhibitor of Bcl-2, Bxl-xl, and Bcl-ω. ABT-737 exhibits anticancer chemotherapeutic and antithrombotic activities. ABT-737 is currently in clinical trials as…
ABT-263 ABT-263 is a BH3 mimetic that inhibits Bcl-2, Bcl-ω, and Bcl-xl. ABT-263’s inhibition of Bcl-xl results in thrombocytopenia by inducing apoptotic death of platelets, limiting its usage. ABT-263 exhibits…
ABT-199 ABT-199 is a BH3 mimetic that inhibits Bcl-2 but does not affect Bcl-xl. ABT-199 exhibits anticancer chemotherapeutic activity, inducing Bim-mediated apoptosis in chronic lymphocytic leukemia (CLL) cells. ABT-199 also…