Suramin Hexasodium
Suramin Hexasodium Suramin is an inhibitor of GPCRs; it prevents guanine nucleotide exchange. Suramin inhibits SIRT, telomerase, and P2Y receptors; it also acts as an agonist at Ryanodine (RyR) receptors.…
June 2017
Sumatriptan Succinate
Sumatriptan Succinate Sumatriptan is a tryptamine agonist at 5-HT1B/1D receptors that is clinically used to treat migraines. Sumatriptan exhibits vasoconstrictive and gastrointestinal motility modulating activities. The anti-migraine activity of sumatriptan…
Sulindac Sulfone
Sulindac Sulfone Sulindac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2. Sulindac exhibits anti-inflammatory, tocolytic, neuroprotective, anti-metastatic, and anticancer chemotherapeutic activities. In vitro, sulindac inhibits phosphodiesterases (PDEs),…
Sulindac Sulfide
Sulindac Sulfide Sulindac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2. Sulindac exhibits anti-inflammatory, neuroprotective, anti-metastatic, and anticancer chemotherapeutic activities. In vitro, sulindac inhibits phosphodiesterases (PDEs), increasing…
Sulindac
Sulindac Sulindac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2. Sulindac exhibits anti-inflammatory, tocolytic, neuroprotective, anti-metastatic, and anticancer chemotherapeutic activities. In vitro, sulindac inhibits phosphodiesterases (PDEs), increasing…
Sulfluramid
Sulfluramid Sulfluramid is a perfluorinated pesticide that exhibits insecticidal activity against Rhinotermidae and Blattellidae. In vivo, sulfluramid displays immunosuppressive activity, decreasing production of IgM. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18974171 Cas No. 4151-50-2…
Sulfasalazine
Sulfasalazine Sulfasalazine is a mesalazine derivative sulfa drug that exhibits anti-inflammatory, immunomodulatory, analgesic, antioxidative, neuromodulatory, and anti-fibrotic activities. Sulfasalazine is clinically used to treat rheumatoid arthritis, inflammatory bowel disease, and…
Sulfamethoxazole
Sulfamethoxazole Sulfamethoxazole is a sulfonamide antibiotic that competitively inhibits PABA, preventing bacterial production of folic acid and synthesis of DNA. Sulfamethoxazole displays antibacterial activity against Streptococcus, Staphylococcus, Escherichia, Haemophilus, and…
Sulfadoxine
Sulfadoxine Sulfadoxine is a sulfonamide anti-parasitic that inhibits dihydropteroate synthase, preventing folate synthesis and increases blood oxygen levels. Sulfadoxine exhibits antimalarial activity and is typically given with pyrimethamine. References PubMed…
Sulfadimethoxine
Sulfadimethoxine Sulfadimethoxine is a sulfonamide antibiotic that inhibits folic acid synthesis; it displays antibacterial efficacy in the treatment of various bacterial infections. Sulfadimethoxine is photodegraded by UV light. References PubMed…