TAK-632
TAK-632 TAK 632 is a benzothiazole pan-Raf inhibitor that displays anticancer chemotherapeutic activity. TAK 632 induces dimerization of Raf but prevents kinase activity. This compound inhibits cellular proliferation of melanoma…
June 2017
TAE-226
TAE-226 TAE-226 is an inhibitor of focal adhesion kinase (FAK) that exhibits anti-angiogenic and anticancer activities. In vitro, this compound inhibits angiogenesis, decreases the viability of cancer cells, and suppresses…
Tacrolimus
Tacrolimus Tacrolimus is a calcineurin inhibitor that exhibits immunosuppressive, anti-fibrotic, anti-inflammatory, and anti-allergic activities. Clinically, tacrolimus is used to treat atopic dermatitis and conjunctivitis. In vivo, tacrolimus inhibits synthesis of…
T2 Triol
T2 Triol T2 triol is a Fusarium trichothecene mycotoxin. In vitro, this compound displays significant cytotoxic activity, inducing breakdown of polyribosomes and inhibiting polypeptide chain elongation in eukaryotes. Additionally, T2…
T2 Toxin
T2 Toxin T2 toxin is a trichothecene mycotoxin initially produced by species of Fusarium. T2 toxin is often found in grains and grain products such as cereals and breads. T2…
T2 Tetraol
T2 Tetraol T4 tetraol is a trichothecene mycotoxin found in Fusarium. Like other trichothecene mycotoxins, T4 tetraol is cytotoxic, although it displays lower levels of toxicity than other similar compounds.…
Systemin
Systemin Systemin is an 18-amino acid peptide hormone originally found in the leaves of tomato plants, as well as other plants in the Solanaceae family. Systemin increases expression of defense-related…
Syntide 2
Syntide 2 Syntide 2 is a synthetic 15-amino acid peptide. Syntide 2 is a substrate of Ca2+-dependent protein kinase (CDPK), CaMKII, PKC, and other kinases involved in Ca2+ signaling. Syntide…
Synephrine
Synephrine Synephrine is an endogenous alkaloid that can also be found in citrus fruits, Evodia, and Zanthoxylum. Synephrine exhibits vasoconstrictive, anti-inflammatory, antibacterial, and gastrointestinal motility modulating activities. Synephrine acts as…
Swainsonine
Swainsonine Swainsonine is an indolizidine alkaloid isolated from the fungus metharhizium anisopliae. It is an antineoplastic immunomodulator. Swainsonine restores the capacities of immunodeficient mice such that the growth and metastasis…