Bafilomycin B1
Bafilomycin B1 Bafilomycin B1 is a macrolide antibiotic that also exhibits antifungal activity. Bafilomycin B1 inhibits the vacuolar H+ ATPase. Additionally, bafilomycin B1 inhibits Foxo1 and increases β cell apoptosis,…
June 2017
Bafilomycin A1
Bafilomycin A1 Bafilomycin A1 is a macrolide antibiotic initially produced by Streptomyces that exhibits anti-parasitic, antimalarial, and anticancer chemotherapeutic activities. Bafilomycin A1 inhibits the vacuolar H+ ATPase and suppresses autophagy.…
Bactenecin
Bactenecin Bactenecin is a cathelicidin-derived antimicrobial peptide (AMP) found in bovine neutrophils. Bactenecin exhibits antibiotic activity, increasing membrane permeability and inhibiting growth. Bactenecin is an effective antibacterial peptide, displaying activity…
Baclofen
Baclofen Baclofen is a GABA derivative that acts as an agonist at GABA-B receptors; it is commonly used in animal models to examine the effects of GABAergic neurotransmission in a…
Baccatin III
Baccatin III Baccatin III is a diterpene found in Taxus and various fungal organisms that exhibits immunomodulatory and anticancer chemotherapeutic activities. Unlike most taxanes, baccatin III does not bind tubulin;…
B-type Natriuretic Peptide (1-32), rat
B-type Natriuretic Peptide (1-32), rat Brain natriuretic peptide (BNP) binds the natriuretic peptide receptor type B (NPR-B) to exert cardiomodulatory activity. BNP is secreted by the heart; it displays lipolytic…
B-type Natriuretic Peptide (1-32), human
B-type Natriuretic Peptide (1-32), human Brain natriuretic peptide (BNP) binds the natriuretic peptide receptor type B (NPR-B) to exert cardiomodulatory activity. BNP is secreted by the heart; it displays lipolytic…
B-Raf IN 1
B-Raf IN 1 B-Raf IN 1 inhibits both B-Raf and c-Raf, likely displaying anticancer activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842813 Cas No. 950736-05-7 Purity ≥98% Formula C29H24F3N5O Formula Wt. 515.54 IUPAC Name…
Azelastine Hydrochloride
Azelastine Hydrochloride Azelastine is a second generation antihistamine that inhibits H1 histamine receptors. Azelastine exhibits anti-allergic, anti-inflammatory, and anti-tussive activities and is clinically used to treat allergic rhinitis. Azelastine activates…
AZD-8330
AZD-8330 AZD-8330 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. AZD-8330 is currently in clinical trials for the treatment of advanced stage cancers. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18842808 Cas No.…