Dabrafenib
Dabrafenib Dabrafenib is a reversible kinase inhibitor with anticancer chemotherapeutic activity. This compound is selective primarily for mutant (V600E) B-Raf, but has also inhibited tumor growth in cells expressing other…
June 2017
D(+)-Trehalose Dihydrate
D(+)-Trehalose Dihydrate Trehalose is a natural α-linked disaccharide composed of α-glucose units that is found in plants, animals, bacteria, and fungi. Trehalose has high water retention capabilities and can be…
D,L-α-Lipoic Acid
D,L-α-Lipoic Acid Thioctic/lipoic acid is an endogenous organosulfur that exhibits antioxidative activity. This compound is commercially used as a dietary supplement and can be found in meat and leafy vegetables.…
D,L-Tetrahydropalmatine
D,L-Tetrahydropalmatine D,L-Tetrahydropalmatine is an alkaloid found in Corydalis and Stephania that exhibits analgesic, antinociceptive, anxiolytic, antidepressant, and anti-parasitic activities. This compound inhibits D1/2 receptors and may also inhibit L-type Ca2+…
D,L-Naproxen
D,L-Naproxen Naproxen is a propionic non-steroidal anti-inflammatory drug (NSAID) that exhibits antipyretic, analgesic, anti-inflammatory, and antiviral activities. Naproxen inhibits COX-1 and COX-2 and is clinically used to treat fever, swelling,…
D,L-Homocysteine Thiolactone Hydrochloride
D,L-Homocysteine Thiolactone Hydrochloride D,L-Homocysteine thiolactone binds to and induces conformational changes in various plasma proteins. This compound slows coagulation and causes more tightly packed fibrin structure formation; it is detrimental…
D,L-Aminoglutethimide
D,L-Aminoglutethimide D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease. References…
D,L-1′-Acetoxychavicol Acetate
D,L-1′-Acetoxychavicol Acetate 1’-Acetoxychavicol acetate (ACA) was originally found in Alpinia galanga; it exhibits anti-obesity, immunomodulatory, anti-inflammatory, anti-asthma, anti-allergic, antibiotic, antiviral, anti-parasitic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities. ACA activates…
D-Tetrahydropalmatine
D-Tetrahydropalmatine D-Tetrahydropalmatine is an alkaloid originally found in Corydalis. D-Tetrahydropalmatine inhibits D1 receptors, but unlike its optical L isomer, has no affinity for D2 receptors. This compound also inhibits the…
D-Sphingosine
D-Sphingosine D-Sphingosine is an endogenous component of sphingolipids that exhibits antibacterial activity against many gram positive and gram negative bacteria such as Escherichia, Staphylococcus, and Corynebacterium. D-Sphingosine also inhibits PKC.…