Desmopressin Desmopressin is a synthetic peptide derivative of arginine vasopressin that binds and activates vasopressin-2 receptors (V2Rs). Desmopressin exhibits pro-coagulant/pro-thrombotic and antidiuretic activities and is clinically used to treat bleeding…
Dermorphin Analog This synthetic peptide analog of dermorphin activates μ-opioid receptors (μORs) and δ-opioid receptors (δORs). Like other similar opioid agonists, this peptide affects learning and memory as well as…
Dermaseptin I Dermaseptin is a cationic antimicrobial peptide (AMP) that exhibits antibacterial activity against Acinetobacter and Pseudomonas. Dermaseptin increases permeability of cell membranes. Dermaseptin also exhibits anticancer chemotherapeutic and anti-angiogenic…
Dehydroandrographolide Dehydroandrographolide is a labdane diterpene found in Andrographis that exhibits antiviral, antioxidative, and anti-inflammatory activities. In vitro, this compound inhibits hepatitis B virus replication. Additionally, dehydroandrographolide decreases LPS-induced expression…
DCC-2036 DCC-2036 (rebastinib) is an Abl inhibitor that exhibits anticancer activity. In cellular models of chronic myelogenous leukemia (CML), rebastinib induces apoptosis and inhibits cell proliferation. Rebastinib binds the switch…
Dapiprazole Hydrochloride Dapiprazole is an α1-adrenergic antagonist that displays preference for α1A and α1D receptors over α1B receptors. Dapiprazole is used as a miotic compound, evoking pupillary constriction and reversing…
Dantrolene Sodium Heptahydrate Dantrolene is a hydantoin derivative that inhibits the ryanodine receptor (RyR), preventing mitochondrial Ca2+ uptake. Dantrolene also inhibits L-type Ca(V)1.1 Ca2+ channels and is clinically used to…
Dansyl-YVG Dansyl YVG is a peptide substrate of peptidylglycine monooxygenase and peptidylglycine α-amidating enzyme. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18856006 Purity ≥95% Formula C28H34N4O7S Formula Wt. 571.63 Bauman AT, Yukl ET, Alkevich K,…
Dacarbazine Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer. References…
Dabrafenib Mesylate Dabrafenib is a reversible kinase inhibitor with anticancer chemotherapeutic activity. This compound is selective primarily for mutant (V600E) B-Raf, but has also inhibited tumor growth in cells expressing…