ELR-510444 ELR-510444 inhibits microtubule polymerization through binding tubulin at the colchicine site; it exhibits anti-angiogenic and anticancer chemotherapeutic activities. ELR-510444 inhibits cell proliferation and tumor growth in models of breast…
Ellagic Acid Ellagic acid is a phenol found in various fruits that exhibits neuroprotective, anti-angiogenic, anti-inflammatory, anti-asthma, anti-allergic, antiviral, antioxidative, anti-parasitic, antimalarial, anticancer, and anti-ulcerative activities. Ellagic acid inhibits HIF-1α-induced…
Elcatonin Acetate Elcatonin is a synthetic analog of eel calcitonin that exhibits analgesic, anti-allodynic, antacid, and anti-resorptive activities. In animal models, elcatonin inhibits the effects of thermal and mechanical pain;…
Ebselen Ebselen is a synthetic glutathione peroxidase mimetic that reacts with cysteine residues; it exhibits antimicrobial, antibacterial, anti-diabetic, and antioxidative activities. Ebselen increases ROS and mitochondrial membrane potential, inhibiting GDH…
Ebastine Ebastine is a second-generation antihistamine and anti-inflammatory compound that is clinically used to treat allergic rhinitis. Like other newer antihistamines, administration of ebastine results in less of a sedative…
E64-d E64d is an inhibitor of cathepsins that exhibits neuroprotective activity. In vivo, E64d inhibits cathepsin D, decreasing brain amyloid-β (Aβ) plaque formation. E64d inhibition of cathepsins also aggravates left…
E64 E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1889806 Cas No. 66701-25-5 Purity ≥98% Formula C15H27N5O5 Formula Wt. 357.41 IUPAC Name…
E-JIB-04 This compound is the E stereoisomer of JIB-04, an inhibitor of Jumonji family histone demethylases; it does not inhibit activity of α-ketoglutarate. JIB-04 exhibits anticancer chemotherapeutic activity, inhibiting protein…
Dynasore Dynasore is an inhibitor of dynamin, a protein involved in membrane fission during endocytosis; it displays anti-resorptive, anti-osteoporotic, and antiviral activities. Dynasore inhibits bone resorption by preventing actin ring…
Droloxifene Droloxifene is an anti-estrogen triphenylthylene selective estrogen receptor modulator (SERM); it is an analog of tamoxifen. Droloxifene acts as an estrogen receptor agonist in bone and as an estrogen…