Endothelin-3, human Endothelin-3 is an endogenous peptide agonist at endothelin B (ET-B) receptors that exhibits anti-inflammatory, neuromodulatory, and pro-angiogenic activities. In animal models, endothelin-3 inhibits platelet-activating factor-induced edema. In other…
Endothelin-2, human Endothelin-2 is an endogenous peptide agonist at endothelin A and B (ET-A/B) receptors that exhibits anti-angiogenic and vasoconstrictive activities. Endothelin-2 inhibits endothelial cell migration and invasion, suppressing vascular…
Endothelin-1, human Endothelin-1 is an endogenous peptide agonist at endothelin A and B (ET-A/B) receptors that exhibits anti-angiogenic and vasoconstrictive activities. Endothelin-1 decreases tube formation and PPARγ expression in pulmonary…
Endonuclease Antigenic Site This peptide is an analog of a sequence of HIV-1 for which cytotoxic T lymphocytes may bind. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18904219 Purity ≥98% Formula C108H167N27O29 Formula Wt. 2307.67…
Endomorphin-2 Endomorphin-2 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-2 increases pain thresholds in animal models of thermal…
Endomorphin-1 Endomorphin-1 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-1 increases pain thresholds in animal models of thermal…
Enalaprilat Dihydrate Enalaprilat is the active metabolite of enalapril. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits…
EMD 1214063 EMD 1214063 is an inhibitor of c-MET that exhibits anticancer chemotherapeutic activity. In animal models of hepatocellular carcinoma, EMD 1214063 inhibits tumor growth and induces complete regression. In…
Emamectin B1 Benzoate Emamectin B1 is a semi-synthetic avermectin that is clinically used in veterinary medicine; it exhibits anti-helminthic and anti-parasitic activities. Like other avermectins, emamectin increases GABA release, causing…
Elvitegravir Elvitegravir is an antiviral compound that inhibits integrase activity. This compound is clinically used to treat HIV infection. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1890122 Cas No. 697761-98-1 Purity ≥98% Formula C23H23ClFNO5 Formula…