GDC-0623
GDC-0623 GDC-0623 is an inhibitor of MEK that prevents MEK-dependent B-Raf and KRAS signaling. GDC-0623 exhibits anticancer chemotherapeutic activity and is currently in clinical trials as a potential treatment for…
June 2017
GDC-0449
GDC-0449 GDC-0449 is an inhibitor of Smo that prevents downstream hedgehog (Hh) signaling. GDC-0449 exhibits anticancer chemotherapeutic activity; it is currently approved to treat basal cell carcinoma and is in…
GDC-0349
GDC-0349 GDC-0349 is an ATP-competitive inhibitor of mTOR that exhibits anticancer chemotherpeutic activity. GDC-0349 displays pre-clinical efficacy in vitro and in vivo. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18926277 Cas No. 1207360-89-1 Purity ≥98%…
Gatifloxacin Sesquihydrate
Gatifloxacin Sesquihydrate Gatifloxacin is a fluoroquinolone antibiotic that inhibits DNA gyrase. Gatifloxacin exhibits antibacterial efficacy against Mycobacterium and Streptococcus, treating tuberculosis and pneumonia. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18926245 Cas No. 180200-66-2 Purity…
Gastrin Releasing Peptide, human
Gastrin Releasing Peptide, human Gastrin-releasing peptide (GRP) is an endogenous bombesin-like peptide that stimulates the release of gastrin by binding GRP receptors; it is involved in feeding behavior (acting as…
Gastrin I, human
Gastrin I, human Gastrin I, like gastrin, acts as an agonist at the cholestocystokinin 2 (CCK2) receptor, exhibiting anorexigenic and gastrointestinal motility modulating activities. Gastrin is an endogenous peptide that…
Gallic Acid
Gallic Acid Gallic acid is a phenol found in various plants including sumac, oak, and witch hazel; it exhibits neuroprotective, antioxidative, anticancer, anti-metastatic, antibiotic, antacid, and anti-ulcerative activities. Gallic acid…
Furosemide
Furosemide Furosemide is a loop diuretic that is clinically used to treat congestive heart failure, edema, and hypertension; it inhibits the Na+/K+/Cl2- (NKCC) symporter and CFTR Cl- channels in the…
Fumonisin B2
Fumonisin B2 Fumonisin B2 is a mycotoxin initially produced by Fusarium that is found as a contaminant in grain, maize, and grapes. Fumonisin B2 inhibits sphingosine acyltransferase, disrupting sphingolipid metabolism.…
Fumonisin B1
Fumonisin B1 Fumonisin B1 is a mycotoxin initially produced by Fusarium that is found as a contaminant in grain, maize, and grapes. Fumonisin B1 inhibits sphingosine acyltransferase, disrupting sphingolipid metabolism.…