Geniposidic Acid Geniposidic acid is an iridoid glucoside found in Eucommia, Castilleja, Plantago, and Gardenia species; it displays antihypertensive, anti-obesity, anti-inflammatory, antioxidative, and anticancer chemotherapeutic properties. In vivo, geniposidic acid…
Geniposide Geniposide is an iridoid glycoside found in species of Gardenia that exhibits antioxidative, anti-diabetic, anti-inflammatory, neuroprotective, antiviral, and antithrombotic activities. Geniposide induces phase II enzymes and increases expression of…
Genipin Genipin is an iridoid glycoside compound found in zhishi or Gardenia jasminoides; it is most well known for its protein cross-linking ability. Genipin displays anti-amnestic, wound healing, anticancer, neuroprotective,…
Gemifloxacin Mesylate Gemifloxacin is a fluoroquinolone antibiotic that displays antibacterial activity against both gram positive and gram negative bacteria. Gemifloxacin is commonly used as a short course of treatment for…
Gemfibrozil Gemfibrozil is a fibrate that exhibits anti-hyperlipidemic and antibacterial activities. Gemfibrozil activates PPARα, increasing synthesis of lipoprotein lipase, which results in decreases in serum total cholesterol, VLDL, LDL, and…
Gemcitabine Hydrochloride Gemcitabine is a 2’-deoxycytidine analog antimetabolite that inhibits ribonucleotide reductase and DNA synthesis. Gemcitabine exhibits anticancer chemotherapeutic and antiviral activities. In pancreatic cancer cells, gemcitabine induces cell death…
Geldanamycin Geldanamycin is an inhibitor of heat shock protein 90 (HSP90) that exhibits antiviral, neuroprotective, and anticancer activities. Geldanamycin decreases viral titers and inflammation in animal models of Chikungunya virus…
Gefitinib Gefitinib is an anticancer chemotherapeutic compound that inhibits mutant isoforms of EGFR. Across a variety of cancer cell lines, gefitinib increases poly(ADP)-ribose polymerase (PARP) cleavage and apoptosis, resulting in…
GDC-0980 GDC-0980 is an inhibitor of PI3K and mTORC1/2 that exhibits anticancer chemotherapeutic and anti-angiogenic activities. GDC-0980 inhibits cell growth in uterine serous carcinoma cells and decreases vascular density by…
GDC-0879 GDC-0879 is an orally bioavailable kinase inhibitor that exhibits anticancer chemotherapeutic activity in vitro and in vivo. GDC-0879 inhibits mutant (V600E) B-Raf, a mutation common to many types of…