MCE inhibitors

For the human Buzz protein (course II), the corresponding mutant protein catalyzed in vitro AMP transfer to the tiny GTPases Rac1 and Cdc42, whilst only marginal impact was observed with the wild-kind proteins [8]

Adenylyl transferases (ATases) utilize adenosine triphosphate (ATP) to covalently modify proteins, nucleic acids, or tiny molecules with adenosine monophosphate (AMP), a reaction regarded as adenylylation or AMPylation. The ubiquitous FIC…