Valdecoxib
Valdecoxib Valdecoxib is a COX inhibitor specific for COX-2; it also inhibits carbonic anhydrase. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities. In addition to…
Ubiquitin Ligase- ubiquitin-ligase
Valsartan
Valsartan Valsartan is an angiotensin II (ATII) type 1 receptor (AT1) inhibitor that is clinically used to lower blood pressure and coronary resistance, and to decrease cardiac hypertrophy. Valsartan exhibits…
Vardenafil Dihydrochloride
Vardenafil Dihydrochloride Vardenafil is a centrally-acting phosphodiesterase 5 (PDE5) inhibitor that is clinically used to treat erectile dysfunction. Vardenafil also exhibits antioxidative and antihypertensive activities and shows some potential for…
Vasoactive Intestinal Peptide
Vasoactive Intestinal Peptide Vasoactive intestinal peptide (VIP) is an endogenous peptide hormone that exhibits bronchodilatory, vasodilatory, and immunomodulatory activities. VIP increases levels of IL-10, Foxp3, and TGF-β in vivo and…
Vasoactive Intestinal Peptide, guinea pig
Vasoactive Intestinal Peptide, guinea pig Vasoactive intestinal peptide (VIP) exhibits bronchodilatory, vasodilatory, and immunomodulatory activities. VIP increases levels of IL-10, Foxp3, and TGF-β in vivo and prevents LPS-induced expression of…
Vatalanib Dihydrochloride
Vatalanib Dihydrochloride Vatalanib is an inhibitor of VEGFR that is currently in clinical trials for the treatment of myelodysplastic syndrome, lymphomas, non-small cell lung cancers (NSCLCs), and other cancers. Vatalanib…
VE-821
VE-821 VE-821 is an inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase, a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.…
Vecuronium Bromide
Vecuronium Bromide Vecuronium is a non-depolarizing muscle relaxant that inhibits nicotinic acetylcholine receptors (nAChRs), blocking neurotransmission at the neuromuscular junction. Vecuronium is clinically used as an anesthetic and paralytic during…
Veliparib
Veliparib Veliparib is an oral poly(ADP-ribose) polymerase (PARP) inhibitor that shows anticancer chemotherapeutic and anti-inflammatory activities. Veliparib crosses the blood-brain barrier with a 3:1 plasma:brain drug ratio. Inhibition of PARP…
Vemurafenib
Vemurafenib Vemurafenib is a first generation selective B-Raf inhibitor that has been approved for clinical use in treating unresectable or metastatic melanoma; it exhibits anticancer chemotherapeutic activity. Vemurafenib binds the…