Systemin
Systemin Systemin is an 18-amino acid peptide hormone originally found in the leaves of tomato plants, as well as other plants in the Solanaceae family. Systemin increases expression of defense-related…
Ubiquitin Ligase- ubiquitin-ligase
T2 Tetraol
T2 Tetraol T4 tetraol is a trichothecene mycotoxin found in Fusarium. Like other trichothecene mycotoxins, T4 tetraol is cytotoxic, although it displays lower levels of toxicity than other similar compounds.…
T2 Toxin
T2 Toxin T2 toxin is a trichothecene mycotoxin initially produced by species of Fusarium. T2 toxin is often found in grains and grain products such as cereals and breads. T2…
T2 Triol
T2 Triol T2 triol is a Fusarium trichothecene mycotoxin. In vitro, this compound displays significant cytotoxic activity, inducing breakdown of polyribosomes and inhibiting polypeptide chain elongation in eukaryotes. Additionally, T2…
Tacrolimus
Tacrolimus Tacrolimus is a calcineurin inhibitor that exhibits immunosuppressive, anti-fibrotic, anti-inflammatory, and anti-allergic activities. Clinically, tacrolimus is used to treat atopic dermatitis and conjunctivitis. In vivo, tacrolimus inhibits synthesis of…
TAE-226
TAE-226 TAE-226 is an inhibitor of focal adhesion kinase (FAK) that exhibits anti-angiogenic and anticancer activities. In vitro, this compound inhibits angiogenesis, decreases the viability of cancer cells, and suppresses…
TAK-632
TAK-632 TAK 632 is a benzothiazole pan-Raf inhibitor that displays anticancer chemotherapeutic activity. TAK 632 induces dimerization of Raf but prevents kinase activity. This compound inhibits cellular proliferation of melanoma…
TAK-733
TAK-733 TAK-733 is an inhibitor of MEK that exhibits anticancer chemotherapeutic activity. In tumor explant models, TAK-733 induces tumor regression. In colorectal cancer cells and melanoma cells, this compound suppresses…
Tamibarotene
Tamibarotene Tamibarotene is an agonist at retinoic acid receptors (RARs) and is selective primarily for RARα/β. Tamibarotene exhibits neuroprotective, cognition enhancing, immunomodulatory, and anticancer chemotherapeutic benefits. Tamibarotene upregulates tropomysin-related kinase…
Tamoxifen Citrate
Tamoxifen Citrate Tamoxifen is a selective estrogen receptor modulator (SERM) that acts as an ER agonist in the endometrium and as an ER antagonist in breast tissue; it also inhibits…