Sedanolide
Sedanolide Sedanolide is a phthalide found in celery seeds that exhibits anti-inflammatory, antifungal, anti-parasitic, and nematocidal activities. Sedanolide inhibits COX-1 and COX-2 as well as topoisomerase I and topoisomerase II…
Ubiquitin Ligase- ubiquitin-ligase
Selumetinib
Selumetinib Selumetinib is an orally bioavailable noncompetitive inhibitor of MEK1/2; it primarily displays immunosuppressive and anticancer chemotherapeutic activities. In cellular and animal models of cancer, selumetinib downregulates MAPK activation and…
Senegenin
Senegenin Senegenin is found in Polygata tennifolia; it increases NR2B NMDA receptor subunit expression in the hippocampus, showing benefit as a potential treatment for cognitive dysfunction. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18971914 Cas…
Seratrodast
Seratrodast Seratrodast is an inhibitor of the thromboxane A2 receptor and exhibits anti-asthma and anti-inflammatory activity but no anti-platelet benefits. Seratrodast is used clinically to treat asthma, preventing bronchial hyperresponsiveness…
Sermorelin Acetate
Sermorelin Acetate Sermorelin is a synthetic 28-amino acid peptide analog of growth hormone-releasing hormone (GHRH). Sermorelin exhibits immunomodulatory and pro-angiogenic activities. In vivo, sermorelin stimulates secretion of growth hormone from…
Sertraline Hydrochloride
Sertraline Hydrochloride Sertraline exhibits antidepressant and anxiolytic activities; it is a typical selective serotonin reuptake inhibitor (SSRI). Sertraline primarily inhibits the 5-HT transporter (SERT), but also inhibits the dopamine transporter…
Serum Thymic Factor
Serum Thymic Factor Serum thymic factor (FTS) is a synthetic nonapeptide hormone that exhibits anti-apoptotic, anti-diabetic, anti-inflammatory, and immunomodulatory activities. In vivo, FTS increases activity of superoxide dismutase (SOD) and…
Sesamin
Sesamin Sesamin is a lignin extracted from the seeds of the Sesamin indicum plant. Sesamin exhibits antioxidative and anticancer activities. In cellular models, sesamin suppresses STAT3 signaling, promoting cell cycle…
SFLLR
SFLLR SFLLR is a peptide agonist of protease-activated receptor type 1 (PAR1, also known as the thrombin receptor) that induces platelet adhesion and aggregation, mimicking the effects of thrombin. SFLLR…
SGX-523
SGX-523 SGX-523 is an inhibitor of MET that exhibits anticancer chemotherapeutic activity. SGX-523 inhibits growth of cells and tumors in models of non-small cell lung cancer (NSCLC). SGX-523 also improves…