Raltegravir
Raltegravir Raltegravir is an antiviral compound that inhibits HIV integrase; it is clinically used to treat HIV infection. In pre-clinical models, raltegravir decreases infection rates by preventing insertion of HIV-1…
Ubiquitin Ligase- ubiquitin-ligase
Raltitrexed
Raltitrexed Raltitrexed is a quinazoline analog of folate. Raltitrexed acts as an antifolate anticancer chemotherapeutic, inhibiting thymidylate synthase. Raltitrexed disrupts DNA synthesis and induces strand breaks. This compound is approved…
Ramatroban
Ramatroban Ramatroban is a thromboxane A2 (TxA2) receptor inhibitor that exhibits anti-allergic and anti-inflammatory properties. Ramatroban also competitively inhibits chemoattractant receptor-homologous molecule on Th2 cells (CRTH2), a relatively new prostaglandin…
Ramipril
Ramipril Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits anti-arrhythmic, antihypertensive, and cardioprotective activities. In animal models of myocardial infarction, ramipril decreases ventricular tachycardia and ventricular fibrillation. In other,…
Ramoplanin
Ramoplanin Ramoplanin is a peptide antibiotic that displays antibacterial activity against aerobic and anaerobic gram positive bacteria such as Clostridium difficile. Ramoplanin inhibits bacterial growth by binding lipid II and…
Ramosetron
Ramosetron Ramosetron is an inhibitor of 5-HT3 receptors that is currently in clinical trials as a treatment for chemotherapeutic-induced or postoperative nausea and vomiting; it also treats inflammatory bowel syndrome…
Ranatensin
Ranatensin Ranatensin is a peptide originally found in amphibian skin that exhibits gastrointestinal motility modulating activity. Ranatensin stimulates Cl- secretion in the jejunum in a GRP-related manner. Ranatensin also stimulates…
Ranatensin R
Ranatensin R Ranatensin R is a peptide originally found in amphibian skin. Ranatensin R is an analog of ranatensin, a peptide homologous to neuromedin B. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18957524 Cas No.…
Ranitidine Hydrochloride
Ranitidine Hydrochloride Ranitidine is an inverse agonist at H2 histamine receptors, inducing receptor desensitization and inhibiting downstream signaling. Ranitidine displays antacid activity and is clinically used to treat peptic ulcer…
Ranolazine Dihydrochloride
Ranolazine Dihydrochloride Ranolazine exhibits anti-anginal, anti-arrhythmic, and cardioprotective activities; it is clinically used to treat angina pectoris. Ranolazine inhibits the late Na+ current (Nav1.7 and Nav1.7 channels) and subsequent intracellular…