Puupehenone
Puupehenone Puupehenone is a sesquiterpene found in marine sponges that displays some antioxidative and antiangiogenic activities. In separate cellular models, puupehenone inhibits cell growth and also decreases radical generation by…
Ubiquitin Ligase- ubiquitin-ligase
PX-866
PX-866 PX-866 is a wortmannin analog that inhibits PI3K, exhibiting anticancer chemotherapeutic and anti-angiogenic activities. PX-866 is currently in clinical trials as a standalone or combination therapy in the treatment…
Pyr-GR-pNA
Pyr-GR-pNA Pyr-Gly-Arg-pNA is a fluorogenic peptide substrate that is used to measure activity of serine proteases such as kallikrein 8 and tryptase. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18955670 Purity ≥98% Formula C19H26N8O6 Formula…
Pyrantel Pamoate
Pyrantel Pamoate Pyrantel pamoate is a mixture of pyrantel, a thiophene, and pamoic acid. This combination exhibits anti-parasitic/anti-helminthic activities. Pyrantel pamoate acts as a depolarizing neuromuscular junction blocker, activating nicotinic…
Pyrazinamide
Pyrazinamide Pyrazinamide is a nicotinamide analog prodrug that exhibits antibiotic activity, inhibiting bacterial fatty acid synthetase I. Pyrazinamide displays antibacterial efficacy against both active and dormant bacteria, disrupting cell membranes,…
Pyridostatin Hydrochloride
Pyridostatin Hydrochloride Pyridostatin is a G-quadruplex ligand that induces conformation changes in telomere-G-quadruplex complexes and stimulates double-stranded DNA breakage; it also alters telomere function. Pyridostatin displays antiviral and anticancer activities.…
Pyridoxine Hydrochloride
Pyridoxine Hydrochloride Pyridoxine is a derivative of vitamin B6. In a clinical setting, pyridoxine decreases photosensitivity in subjects with erythropoietic protoporphyria. Pyridoxine exhibits antioxidative activity, inhibiting oxidized LDL-induced generation of…
Pyriproxyfen
Pyriproxyfen Pyriproxyfen is a juvenile hormone mimic insecticide that is used to inhibit the development or maturation of insects such as Bemisia. In Daphnia, pyriproxyfen mimics methyl farnesoate, causing overproduction…
Pyronaridine Tetraphosphate
Pyronaridine Tetraphosphate Pyronaridine exhibits antibiotic properties and is clinically used for its antimalarial and anti-parasitic activities against Plasmodium. Pyronaridine inhibits β-hematin formation, binding hematin and preventing glutathione-dependent degradation. References PubMed…
Pyrrolostatin
Pyrrolostatin Pyrrolostatin is a pro-angiogenic free radical scavenger that improves angiogenesis in animal models. Pyrrolostatin is a lipid peroxidation inhibitor originally produced by species of Streptomyces. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18955860 Cas…