Picoplatin
Picoplatin Picoplatin is an analog of cisplatin with a 2-methylpyridine ligand that displays anticancer chemotherapeutic activity. Picoplatin is used to treat non-small cell lung cancer (NSCLC) and is in clinical…
Ubiquitin Ligase- ubiquitin-ligase
Pidotimod
Pidotimod Pidotimod is an immunostimulatory compound often used as an adjuvant. Pidotimod is clinically used to treat acute respiratory tract infections and stimulates both cellular and humoral immunity. In animal…
PIK-293
PIK-293 PIK-293 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K. PIK-293 is the parent compound of PIK-294. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18954321 Cas No. 900185-01-5 Purity ≥98% Formula…
PIK-294
PIK-294 PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18954370 Cas No. 900185-02-6 Purity ≥98% Formula C28H23N7O2…
PIK-75 Hydrochloride
PIK-75 Hydrochloride PIK-75 is an inhibitor of p110α PI3K that exhibits anticancer and anti-inflammatory activities. In breast cancer cells, PIK-75 inhibits cell motility and adhesion in vitro and in vivo.…
PIK-93
PIK-93 PIK-93 is an inhibitor of PI3K that exhibits some selectivity for p110α and p110γ. PIK-93 also inhibits PI4KIIIβ, a phosphatidylinositol enzyme similar to PI3K. PIK-93 decreases translocation of transient…
Pimecrolimus
Pimecrolimus Pimecrolimus is a calcineurin inhibitor that exhibits immunosuppressive, anti-inflammatory, and antinociceptive activities. Pimecrolimus prevents calcineurin from dephosphorylating nuclear factor of activated T cells (NF-AT), inhibiting T cell signaling; this…
Pimobendan
Pimobendan Pimobendan is a cardiovascular drug commonly used to treat congestive heart failure, dilated cardiomyopathy, and chronic valvular heart disease in veterinary medicine. This compound exhibits vasodilatory and antithrombotic activities,…
Pioglitazone Hydrochloride
Pioglitazone Hydrochloride Pioglitazone is a thiazolidinedione that acts as an agonist at PPARα/γ receptors and also binds mitoNEET, a mitochondrial protein involved in energy homeostasis. Pioglitazone exhibits anti-diabetic, antacid, antidepressant,…
Pipemidic Acid
Pipemidic Acid Pipemidic acid is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase; it exhibits antibacterial activity. Pipemidic acid also inhibits ATP-sensitive K+ channels, inducing insulin release in vitro, suggesting…