Novobiocin Sodium
Novobiocin Sodium Novobiocin is an aminocoumarin antibiotic that inhibits the ATPase activity of the B subunit of bacterial DNA gyrase. Novobiocin is most often used in the treatment of methicillin-resistant…
Ubiquitin Ligase- ubiquitin-ligase
NPS-2143 Hydrochloride
NPS-2143 Hydrochloride NPS-2143 is an antagonist at Ca2+-sensing receptors. It displays anti-osteoporotic, neuroprotective, cardioprotective, and antihypertensive activities. This calcilytic increases bone turnover without decreasing bone mineral density. NPS-2143 also inhibits…
NS-11394
NS-11394 NS-11394 is a positive modulator of GABA-A receptor activity that is somewhat specific for α5/3/2 subunits. This compound exhibits analgesic and anxiolytic activities. In vivo, NS-11394 decreases formalin-induced pain…
NSI-189
NSI-189 NSI-189 increases hippocampal volume and stimulates neurogenesis of hippocampal stem cells in vivo and in vitro. This compound may improve consolidation of information from short-term to long-term memory. In…
Okadaic Acid
Okadaic Acid Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and 2A…
Okadaic Acid Ammonium
Okadaic Acid Ammonium Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and…
Okadaic Acid Sodium
Okadaic Acid Sodium Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and…
Olanzapine
Olanzapine Olanzapine is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, panic disorder, anxiety, and Tourette’s syndrome. Olanzapine acts as an antagonist or inverse agonist at D1-4 receptors, 5-HT1A/2/3/6/7…
Olaparib
Olaparib Olaparib is an inhibitor of poly(ADP-ribose) polymerase (PARP 1/2) that prevents DNA repair. Olaparib displays benefit in clinical trials of BRCA mutation-harboring ovarian and breast cancers as well as…
Oleanolic Acid
Oleanolic Acid Oleanolic acid is a triterpenoid originally found in Vigna angularis and Trigonella foenum-graecum. Oleanolic acid exhibits anticancer, anti-inflammatory, anti-allergic, anti-resorptive, and anti-osteoporotic activities. In hypertrophic scar fibroblasts, oleanolic…