Dapiprazole Hydrochloride Dapiprazole is an α1-adrenergic antagonist that displays preference for α1A and α1D receptors over α1B receptors. Dapiprazole is used as a miotic compound, evoking pupillary constriction and reversing…
DCC-2036 DCC-2036 (rebastinib) is an Abl inhibitor that exhibits anticancer activity. In cellular models of chronic myelogenous leukemia (CML), rebastinib induces apoptosis and inhibits cell proliferation. Rebastinib binds the switch…
Dehydroandrographolide Dehydroandrographolide is a labdane diterpene found in Andrographis that exhibits antiviral, antioxidative, and anti-inflammatory activities. In vitro, this compound inhibits hepatitis B virus replication. Additionally, dehydroandrographolide decreases LPS-induced expression…
Dermaseptin I Dermaseptin is a cationic antimicrobial peptide (AMP) that exhibits antibacterial activity against Acinetobacter and Pseudomonas. Dermaseptin increases permeability of cell membranes. Dermaseptin also exhibits anticancer chemotherapeutic and anti-angiogenic…
Dermorphin Analog This synthetic peptide analog of dermorphin activates μ-opioid receptors (μORs) and δ-opioid receptors (δORs). Like other similar opioid agonists, this peptide affects learning and memory as well as…
Desmopressin Desmopressin is a synthetic peptide derivative of arginine vasopressin that binds and activates vasopressin-2 receptors (V2Rs). Desmopressin exhibits pro-coagulant/pro-thrombotic and antidiuretic activities and is clinically used to treat bleeding…
Dexamethasone Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration and maturation…
Dexamethasone Acetate Monohydrate Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration…
Dexamethasone Phosphate Sodium Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration…
Dexrazoxane Dexrazoxane is an iron chelator that exhibits cardioprotective, antioxidative, pro-angiogenic, and anti-parasitic activities. Dexrazoxane decreases superoxide formation and prevents anthracycline-induced cardiotoxicity. In animal models of myocardial infarction, dexrazoxane decreases…