Calcium Folinate Pentahydrate Calcium folinate is commonly co-administered with methotrexate or other similar chemotherapeutics to provide a folate source for some dividing cells, such as bone marrow cells. Calcium folinate…
Calphostin C Calphostin C is an inhibitor of PKC found in Cladosporium. Calphostin C exhibits anticancer activity, inducing apoptosis, increasing JNK and caspase activation, and stimulating PARP cleavage in breast…
Calyculin A Calyculin A is an inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A) that was first found in Discodermia. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18847434 Cas No. 101932-71-2 Purity ≥98% Formula…
Cambinol Cambinol is an inhibitor of sirtuins, particularly sirtuin1. Cambinol exhibits anti-inflammatory and anticancer chemotherapeutic activities. In various cell lines, cambinol suppresses MAPK and MEK signaling and inhibits expression of…
Canertinib Dihydrochloride Canertinib is an irreversible inhibitor of EGFR (HER2/ErbB). This compound is currently in clinical trials as an anticancer chemotherapeutic, displaying activity against a variety of cancers. In a…
Canrenone Canrenone is an active metabolite of spironolactone that acts as an aldosterone antagonist, anti-androgen, and diuretic. Canrenone acts as a partial agonist on the Na+/K+ ATPase. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1884802…
Cantharidin Canthardin is a toxin initially produced by the blister beetle, Canarthis vesicatoria. Canthardin competitively inhibits serine/threonine phosphatases such as protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A). Canthardin…
Canthaxanthin Canthaxanthin is a carotenoid terpene pigment initially found in various sources including plants and fish. Canthaxanthin exhibits immunostimulatory, antioxidative, and chemopreventive activities; it does not display any vitamin A…
Capecitabine Capecitabine is an antifolate anticancer chemotherapeutic that acts as a prodrug of 5-fluorouracil (5-FU), a fluoropyrimidine carbamate that inhibits thymidylate synthase. Capecitabine is converted to 5-FU by thymidine phosphorylase…
Capsaicin, natural Capsaicin is an agonist of transient receptor potential vanilloid (TRPV) channels that was originally found in peppers of the Capsicum genus. Capsaicin exhibits analgesic, anti-inflammatory, anti-obesity, and anticancer…