AEE-788
AEE-788 AEE-788 is an inhibitor of EGFR, HER2, VEGFR2, and FLT3 that exhibits anticancer chemotherapeutic activity. In animal models with ependymoma xenografts, AEE-788 increases survival rates. In acute myelogenous leukemia…
Ubiquitin Ligase- ubiquitin-ligase
Aeroplysinin
Aeroplysinin Aeroplysinin is a marine sponge alkaloid that exhibits antibiotic, anti-angiogenic, and anticancer activities. Aeroplysinin is used by Aplysia sponges as an antibacterial defense mechanism. In endothelial cells and monocytes,…
Aeruginosamide B
Aeruginosamide B Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.…
Aeruginosamide C
Aeruginosamide C Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.…
Aeruginosamide D
Aeruginosamide D Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.…
Aeruginosamide E
Aeruginosamide E Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.…
Aeruginosin 722
Aeruginosin 722 Aeruginosins are tetrapeptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosins inhibit serine proteases and protein phosphatases (PPs). In endothelial cells, aeruginosins decrease levels of…
Afatinib
Afatinib Afatanib is an anticancer chemotherapeutic compound that has been approved to treat advanced lung cancers such as non-small cell lung cancer (NSCLC) and is in clinical trials as a…
Aflatoxicol
Aflatoxicol Aflatoxicol is a mycotoxin that was initially produced by Aspergillus; it is a metabolite of aflatoxin B1. Aflatoxicol is a grain contaminant occasionally found in livestock feed. Like other…
Aflatoxin B1
Aflatoxin B1 Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin B1 is the most cytotoxic of all aflatoxins; it inhibits…