**Background** Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone that plays a critical role in maintaining the stability and function of numerous client proteins, many of which…
Hyaluronic acid (HA) has emerged as a cornerstone in regenerative medicine due to its exceptional biocompatibility, biodegradability, and intrinsic bioactivity. As a major component of the extracellular matrix (ECM), HA…
**Background** Autoinflammatory diseases are characterized by inappropriate activation of the innate immune system, leading to systemic inflammation and tissue damage. Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine that plays a…
Chronic exposure to elevated manganese levels is increasingly recognized as a significant risk factor for neurocognitive and motor impairments, particularly in children. Despite this, the cellular mechanisms underlying manganese toxicity…
**Background** The G protein-coupled receptor 84 (GPR84) is a receptor primarily expressed in immune cells and is activated by medium-chain fatty acids. Activation of GPR84 plays a critical role in…
**Background** Obesity is a complex, chronic disease characterized by excessive adipose tissue accumulation, which significantly increases the risk of cardiovascular diseases, type 2 diabetes, and metabolic syndrome. The management of…
**Background** Fluorescent labeling is a fundamental tool in biomedical research, enabling the visualization and tracking of biomolecules within complex biological systems. Among various labeling strategies, bioorthogonal chemistry has emerged as…
**Background** Hypertension and angina pectoris are prevalent cardiovascular conditions characterized by elevated blood pressure and reduced myocardial oxygen supply, respectively. These conditions often lead to severe complications, including myocardial infarction…
**Background** Fatty amides are a diverse group of lipid-derived compounds that play significant roles in various biological processes, including cell signaling, membrane stabilization, and the modulation of inflammatory responses. These…
**Background** Schizophrenia is a severe and chronic mental disorder characterized by distortions in thinking, perception, emotions, and behavior. For decades, the primary pharmacological approach to treating schizophrenia has focused on…