S-(+)-Ibuprofen
S-(+)-Ibuprofen is the optically active isomer of ibuprofen, a non-steroidal anti-inflammatory drug (NSAID) that non-selectively inhibits COX-1 and COX-2. Ibuprofen exhibits anti-inflammatory, antipyretic, analgesic, and neuroprotective activities. This compound displays protective efficacy against Alzheimer’s disease when administered clinically.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1896926
| Cas No. |
51146-56-6 |
|---|---|
| Purity |
≥98% |
| Formula |
C13H18O2 |
| Formula Wt. |
206.28 |
| Chemical Name |
(+)-2-(4-Isobutylphenyl)-propionic Acid |
| IUPAC Name |
(2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid |
| Melting Point |
51-53°C |
| Solubility |
Soluble in methanol, DMSO and ethanol. |
| Appearance |
White bulb crystalline powder |
Vlad SC, Miller DR, Kowall NW, et al. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6;70(19):1672-7. PMID: 18458226.
Van Esch A, Van Steensel-Moll HA, Steyerberg EW, et al. Antipyretic efficacy of ibuprofen and acetaminophen in children with febrile seizures. Arch Pediatr Adolesc Med. 1995 Jun;149(6):632-7. PMID: 7767417.
