H7
H7 is an inhibitor of PKC and PKG that is used to study the effects of protein kinase signaling in research models.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18930016
| Cas No. |
108930-17-2 |
|---|---|
| Purity |
≥98% |
| Formula |
C14H17N3O2S • 2HCl |
| Formula Wt. |
364.40 |
| IUPAC Name |
5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride |
| Synonym |
(-)-1-(5-Isoquinolinesulfonyl)-2-methylpiperazine di-HCl salt |
| Melting Point |
215-225°C |
| Solubility |
Soluble in water. |
Chen JJ, Zhang J, Cai Y, et al. C-type natriuretic peptide inhibiting vascular calcification might involve decreasing bone morphogenic protein 2 and osteopontin levels. Mol Cell Biochem. 2014 Jul;392(1-2):65-76. PMID: 24710639.
Zhang Y, Bao S, Kuang Z, et al. Urotensin II promotes monocyte chemoattractant protein-1 expression in aortic adventitial fibroblasts of rat. Chin Med J (Engl). 2014 May;127(10):1907-12. PMID: 24824254.
