Glycidamide
Glycidamide is an epoxide metabolite of acrylamide, a food contaminant that exhibits carcinogenic activity. Glycidamide induces DNA adduct formation and A-G and A-T mutations in vivo.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18928385
| Cas No. |
5694-00-8 |
|---|---|
| Purity |
≥98% |
| Formula |
C3H5NO2 |
| Formula Wt. |
87.08 |
| IUPAC Name |
oxirane-2-carboxamide |
| Synonym |
Oxirane-2-Carboxamide |
| Melting Point |
32-34°C |
| Appearance |
Light Orange Solid |
Von Tungeln LS, Doerge DR, Gamboa da Costa G, et al. Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay. Int J Cancer. 2012 Nov 1;131(9):2008-15. PMID: 22336951.
Von Tungeln LS, Churchwell MI, Doerge DR, et al. DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide. Int J Cancer. 2009 May 1;124(9):2006-15. PMID: 19123476.
