Cynomolgus BAFFR/TNFRSF13C Protein 4400

Additional Information:
accession XP_001101623.2|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE|backgroundBAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.|molecular weightThe protein has a predicted MW of 7.7 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Cynomolgus BAFFR/TNFRSF13C Protein 4400proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceBAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.Protein namesBAFF receptor (BAFF-R) (Tumor necrosis factor receptor superfamily, member 13C)Gene namesTNFRSF13C,TNFRSF13C BAFF-R hCG_41562Mass18864DaTarget Relevance information above includes information from UniProt accession: Q5H8V1The UniProt Consortium|