Name :
Human BTLA (31-150) Protein, Mouse IgG2a Fc Tag (MALS verified)
Background :
B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
Biological Activity :
Immobilized Human HVEM, His Tag (Cat. No. HVM-H52E9) at 5 μg/mL (100 μL/well) can bind Human BTLA (31-150), Mouse IgG2a Fc Tag (Cat. No. BTA-H5258) with a linear range of 10-156 ng/mL (QC tested).
Species :
Source :
Human BTLA (31-150), Mouse IgG2a Fc Tag (BTA-H5258) is expressed from human 293 cells (HEK293). It contains AA Lys 31 – Ser 150 (Accession # AAP44003.1 ).
Tag :
Synonyms :
（Synonym）BTLA,CD272
Purity :
（Purity）>95% as determined by SDS-PAGE.
Storage and Stability :
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin Level :
（Endotoxin）Less than 0.1 EU per μg by the LAL method.
Formulation :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Protein Structure :
This protein carries a mouse IgG2a Fc tag at the C-terminus
Refactoring Approach :
Please see Certificate of Analysis for specific instructions.
Protein Labeling :
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