Biotin
Biotin Biotin is a water-soluble B vitamin (vitamin B7) that may be found in many foods but is also administered as a dietary supplement. Biotin is a coenzyme involved in…
2017
Biopterin
Biopterin Biopterin is an endogenous pterin coenzyme that acts as a cofactor for amino acid hydroxylases that produce neurotransmitters and bind NOS to stimulate NO release. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18844327 Cas…
Biochanin A
Biochanin A Biochanin A is an isoflavone/flavonoid found in plants in the Fabaceae family, such as clover, soy, and alfalfa. Biochanin A exhibits anticancer, anti-metastatic, estrogenic, neuroprotective, anti-osteoporotic, antiviral, and…
Big Endothelin-1 (1-38), human
Big Endothelin-1 (1-38), human Big endothelin-1 is a cleavage precursor to endothelin-1; secretion of this peptide is stimulated by angiotensin II (AT II) and thrombin. Like endothelin-1, big endothelin-1 exhibits…
Bifonazole
Bifonazole Bifonazole is an imidazole antifungal that also exhibits anticancer activity. Bifonazole inhibits calmodulin, HMG-CoA reductase, and 14-α demethylase in fungi such as dermatophytes. Bifonazole also decreases cell viability and…
Bicalutamide
Bicalutamide Bicalutimide is an inhibitor of the androgen receptor that exhibits anticancer chemotherapeutic activity. With other anti-androgens, bicalutimide decreases levels of Bcl-2, Bcl-XL, caspase-3, and PARP, induces apoptosis, and inhibits…
Biapenem
Biapenem Biapenem is a carbapenem β-lactam antibiotic. Like other carbapenems, biapenem binds penicillin-binding proteins to inhibit bacterial cell wall synthesis. Biapenem exhibits broad spectrum antibacterial activity and is clinically used…
BI-6727
BI-6727 BI-6727 is a polo-like kinase 1 (PLK1) inhibitor that exhibits anticancer activity. In vitro, BI-6727 induces apoptosis in acute myelogenous leukemia (AML) cells. This compound is currently in clinical…
BI-2536
BI-2536 BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18843938 Cas…
Bezafibrate
Bezafibrate Bezafibrate is a PPARα agonist that is clinically used to lower LDL and triglyceride levels and to increase HDL levels. Bezafibrate exhibits anti-hyperlipidemic, cardioprotective, anti-diabetic, anti-osteoporotic, and anticancer chemotherapeutic…