Colistin Sulphate Colistin is an antimicrobial peptide (AMP); it is a polymixin-family antibiotic initially produced by species of Bacillus. Colistin displays antibacterial efficacy against gram negative bacteria, interacting with the…
Colchicine Colchicine is an anti-inflammatory anti-mitotic compound originally found in Colchicum; it is clinically used to treat gout. Colchicine binds tubulin and inhibits microtubule polymerization, inhibiting inflammasome activation, cytokine generation,…
Coffee Compounds References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18852950 (+)-Etomoxir sodium salt
Coffee Compounds References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18852906 RPC-1063
Coelenterazine, natural Coelenterazine is a luciferin-related compound found in aquatic organisms; it is oxidized by Renilla luciferase, an enzyme derived from the sea pansy, and this reaction can be used…
CO-1686 CO-1686 is an inhibitor of mutant forms of EGFR, including T790M EGFR. CO-1686 exhibits anticancer chemotherapeutic activity, inducing tumor regression in animal models of non-small cell lung cancer (NSCLC)…
CM346 Hydrochloride CM346 may display anxiolytic activity, although it is early in developmental stages. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18852887 Cas No. 173352-39-1 Formula C15H21N3O2S • HCl Formula Wt. 343.87 IUPAC Name 6-Ethoxy-2-{sulfanyl}-1H-benzimidazole…
Clozapine N-oxide Clozapine-N-oxide is a ligand that activates engineered GPCRs called “receptors activated solely by synthetic ligands” (RASSLs) or “designer receptors exclusively activated by designer drugs” (DREADDs); this allows for…
Clozapine Clozapine is an atypical antipsychotic that also exhibits some immunosuppressive activity. Clozapine is clinically used to treat mood disorders. Clozapine binds Kv1.1 channels, prolonging the QT interval and also…
Cloxacillin Sodium Monohydrate Cloxacillin is a β-lactam antibiotic that displays antibacterial efficacy against a variety of species; it is especially active versus Staphylococcus. Like other β-lactam antibiotics, this compound binds…