Cyclovirobuxine D Cyclovirobuxine D is originally found in Buxus and displays cardioprotective and anticancer activities. Cyclovirobuxine inhibits the viability of breast cancer cells, inhibiting phosphorylation of Akt and mTOR and…
Cyclosporin H Cyclosporin H is a cyclosporin metabolite that inhibits the formyl peptide receptor but not calmodulin. Cyclosporin H lacks immunosuppressive activity but inhibits basophil activation. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18854586 Cas…
Cyclosporin D Cyclosporin D is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin D exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and…
Cyclosporin C Cyclosporin C is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin C exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and…
Cyclosporin B Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B…
Cyclosporin A Cyclosporin A is a cyclic peptide that exhibits immunosuppressive activity. Cyclosporin A is clinically used to prevent rejection in organ transplants and to treat or prevent graft-versus-host disease…
Cyclopiazonic Acid Cyclopiazonic acid is an inhibitor of sarco/endoplasmic reticulum Ca2+/ATPase (SERCA) pumps, increasing intracellular Ca2+ levels and altering contractility in smooth muscle tissues. Additionally, this compound inhibits proliferation of…
Cyclophosphamide Monohydrate Cyclophosphamide is a nitrogen mustard that acts as an alkylator, adding alkyl groups to the N7 nitrogen of guanine bases; this inhibits DNA repair and replication. Cyclophosphamide exhibits…
Cyclopamine Cyclopamine is a steroidal jerveratrum alkaloid found in Veratrum that binds Smo, inhibiting hedgehog (Shh) signaling pathways. Cyclopamine exhibits anticancer activity, decreases expression of Gli2 and Bcl-2, inhibiting proliferation…
Cycloheximide Cycloheximide was initially produced by Streptomyces. Cycloheximide inhibits protein synthesis in eukaryotes by preventing tRNA translocation and elongation. Cycloheximide is not used in humans due to its high toxicity.…