DCC-2036
DCC-2036 DCC-2036 (rebastinib) is an Abl inhibitor that exhibits anticancer activity. In cellular models of chronic myelogenous leukemia (CML), rebastinib induces apoptosis and inhibits cell proliferation. Rebastinib binds the switch…
DCC-2036 DCC-2036 (rebastinib) is an Abl inhibitor that exhibits anticancer activity. In cellular models of chronic myelogenous leukemia (CML), rebastinib induces apoptosis and inhibits cell proliferation. Rebastinib binds the switch…
Dapiprazole Hydrochloride Dapiprazole is an α1-adrenergic antagonist that displays preference for α1A and α1D receptors over α1B receptors. Dapiprazole is used as a miotic compound, evoking pupillary constriction and reversing…
Dantrolene Sodium Heptahydrate Dantrolene is a hydantoin derivative that inhibits the ryanodine receptor (RyR), preventing mitochondrial Ca2+ uptake. Dantrolene also inhibits L-type Ca(V)1.1 Ca2+ channels and is clinically used to…
Dansyl-YVG Dansyl YVG is a peptide substrate of peptidylglycine monooxygenase and peptidylglycine α-amidating enzyme. References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18856006 Purity ≥95% Formula C28H34N4O7S Formula Wt. 571.63 Bauman AT, Yukl ET, Alkevich K,…
Dacarbazine Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer. References…
Dabrafenib Mesylate Dabrafenib is a reversible kinase inhibitor with anticancer chemotherapeutic activity. This compound is selective primarily for mutant (V600E) B-Raf, but has also inhibited tumor growth in cells expressing…
Dabrafenib Dabrafenib is a reversible kinase inhibitor with anticancer chemotherapeutic activity. This compound is selective primarily for mutant (V600E) B-Raf, but has also inhibited tumor growth in cells expressing other…
D(+)-Trehalose Dihydrate Trehalose is a natural α-linked disaccharide composed of α-glucose units that is found in plants, animals, bacteria, and fungi. Trehalose has high water retention capabilities and can be…
D,L-α-Lipoic Acid Thioctic/lipoic acid is an endogenous organosulfur that exhibits antioxidative activity. This compound is commercially used as a dietary supplement and can be found in meat and leafy vegetables.…
D,L-Tetrahydropalmatine D,L-Tetrahydropalmatine is an alkaloid found in Corydalis and Stephania that exhibits analgesic, antinociceptive, anxiolytic, antidepressant, and anti-parasitic activities. This compound inhibits D1/2 receptors and may also inhibit L-type Ca2+…