Erythromycin
Erythromycin Erythromycin is a macrolide antibiotic that binds the 50s subunit of bacterial ribosomes, inhibiting protein synthesis by preventing transfer of tRNA from the A site to the P site.…
2017
Erysolin
Erysolin Erysolin is an isothiocyanate (ITC) and analog of sulforaphane found in cruciferous vegetables. Erysolin exhibits antioxidative and anticancer activities. Erysolin induces phase II enzymes and inhibits growth of colon…
Erucin
Erucin Erucin is an isothiocyanate (ITC) and analog of sulforaphane found in cruciferous vegetables. Erucin exhibits antioxidative, anti-inflammatory, neuroprotective, anticancer chemotherapeutic, and chemopreventive activities. Like other ITCs, erucin induces phase…
Erlotinib Hydrochloride
Erlotinib Hydrochloride Erlotinib is an inhibitor of EGFR that exhibits anticancer chemotherapeutic benefit; it is currently in clinical trials for the treatment of colorectal cancer, non-small cell lung cancers (NSCLCs),…
Ergosterol
Ergosterol Ergosterol is a sterol component of cell membranes in yeast and fungi. Ergosterol is a target for many antifungal compounds. Ergosterol exhibits anti-angiogenic, anticancer chemotherapeutic, and chemopreventive activities. In…
Erdosteine
Erdosteine Erdosteine is a thiol derivative that is clinically used to treat bronchitis and chronic obstructive lung diseases; it exhibits mucolytic, antioxidative, and anti-inflammatory activities. In vitro, erdosteine inhibits H2O2-induced…
EPZ6438
EPZ6438 EPZ-6438 is an inhibitor of EZH2, a histone methyltransferase (HMT) responsible for methylation of lysine and arginine residues and controls gene transcription fidelity in cells. EPZ-6438 displays anticancer chemotherapeutic…
EPZ005687
EPZ005687 EPZ-005687 is a highly selective inhibitor of mutant EZH2, a histone methyltransferase (HMT) that exhibits point mutations at key residues Tyr641 and Ala677 in non-Hodgkin’s lymphoma and other cancers.…
EPZ-5676
EPZ-5676 EPZ-5676 is an inhibitor of DOT1L histone methyltransferase (HMT) that exhibits anticancer chemotherapeutic activity. In acute myelogenous leukemia (AML) cells with MLL gene translocations, EPZ-5676 displays cytotoxicity; in similar…
Eptifibatide
Eptifibatide Eptifibatide is an inhibitor of glycoprotein GP IIb/IIIa that exhibits antiplatelet/antithrombotic activity. Eptifibatide inhibits fibrinogen-mediated platelet aggregation and is clinically used to treat acute coronary syndrome. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1892020/…