FLI-06
FLI-06 FLI-06 is a dihydropyridine inhibitor of γ-secretase that suppresses Notch signaling in vitro and in vivo. FLI-06 inhibits protein secretion prior to endoplasmic reticulum exit. Like other Notch signaling…
2017
Fleroxacin
Fleroxacin Fleroxacin is a fluoroquinolone antibiotic that displays antibacterial activity against gram positive and gram negative bacteria. Fleroxacin inhibits bacterial DNA gyrase and helicase. In vitro, fleroxacin inhibits DNA unwinding…
Flavokawain B
Flavokawain B Flavokawain B is a chalcone kavalactone originally found in Piper methysticum (kava plant). Flavokawain B exhibits hepatotoxic and anti-inflammatory activities. This compound inhibits degradation of IκBα and activation…
Flavokawain A
Flavokawain A Flavokawain A is a chalcone kavalactone originally found in Piper methysticum (kava plant). Flavokawain A exhibits anti-inflammatory and anticancer chemotherapeutic activities. This compound inhibits degradation of IκBα and…
Flavanone
Flavanone Flavanone is a flavonoid found in many plant sources. Flavanones exhibit anticancer, antimicrobial, antioxidative, and anti-angiogenic activities. The basic structure of flavanone itself inhibits proliferation of tumor cells. References…
Flag Peptide
Flag Peptide Flag peptide is an octapeptide used to tag proteins and to label or separate particular subsets of proteins from one another using affinity chromatography, fluorescence, or gel electrophoresis.…
Fisetin
Fisetin Fisetin is a flavonoid found in various plant sources that exhibits neuroprotective, cognition enhancing, antioxidative, immunosuppressive, anti-angiogenic, and anticancer activities. In animal models of Alzheimer’s disease, fisetin decreases levels…
Fingolimod Hydrochloride
Fingolimod Hydrochloride Fingolimod is an inhibitor of sphingosine 1-phosphate receptors that is used clinically as a treatment for autoimmune diseases such as multiple sclerosis; this compound prevents movement of autoreactive…
Finasteride
Finasteride Finasteride is an inhibitor of steroid 5-α-reductase that decreases metabolism of testosterone, decreasing cell proliferation and fluid production in the prostate; it is clinically used to treat benign prostatic…
Filipin Complex
Filipin Complex Filipin Complex is a mixture of four components: Filipin I, Filipin II, Filipin III, and Filipin IV. These compounds are 28-membered ring polyene macrolide antifungal antibiotics. Filipin complex…