Mebendazole Mebendazole is a benzimidazole anti-parasitic/anti-helminthic compound that also exhibits anticancer chemotherapeutic activity. Mebendazole inhibits microtubule polymerization in parasitic worms. In melanoma cells, mebendazole decreases levels of Bcl-2 and induces…
MDL 29951 MDL 29951 acts as an agonist at GPR17, inhibiting maturation of primary oligodendrocytes and potentially promoting myelin repair in models of multiple sclerosis. MDL 29951 also inhibits NMDA…
Mdivi-1 Mdivi-1 is a quinazolinone inhibitor of mitochondrial division that prevents mitochondrial fission and exhibits neuroprotective, cardioprotective, and anti-metastatic properties. In spinal cord injury models, Mdivi-1 decreases neuronal apoptosis and…
MC1568 MC1568 interferes with myogenic signaling by blocking HDAC enzymatic activity and MEF2-mediated transactivation in C2C12 cells. Exposure of rat intestinal epithelial cell line EIC-18 to MC1568 prevented stimulation of…
Matrix GLa Protein – pNa Matrix GLa protein inhibits vascular calcification in a vitamin K-dependent manner. Serum levels of this peptide may be used as a biomarker for renal failure,…
Matrine Matrine is an alkaloid found in Sophora that exhibits anticancer chemotherapeutic, antinociceptive, anti-inflammatory, neuroprotective, anti-fibrotic, and antiepileptic/anticonvulsant activities. Matrine increases levels of Bax and decreases levels of Bcl-2 and…
Mastoparan X Mastoparan X is an antimicrobial/antibacterial peptide (AMP) derived from the venom of bees and wasps. Mastoparan X activates mast cells through binding and activation of the Gα subunit…
Mastoparan 8 Mastoparan 8 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps that activates Gi/o GPCRs. Mastoparan 8 is an analog of mastoparan with similar…
Mastoparan 7 Mastoparan 7 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps that activates Gi/o GPCRs, increasing release of downstream signaling messengers such as cAMP,…
Mastoparan 17 Mastoparan 17 is an inactive analog of mastoparan that is often used as a negative control to measure mastoparan activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18941626 Cas No. 145854-61-1 Purity ≥95%…