Meropenem Sodium Carbonate Meropenem is a carbapenem β-lactam antibiotic that inhibits penicillin binding proteins, preventing cell wall synthesis. Meropenem exhibits antibacterial activity against Morganella, Enterobacter, Klebsiella, Mycobacterium, and Bacillus. References…
Men 10376 Men 10376 is a peptide antagonist at neurokinin-2 (NK2) receptors. Men 10376 decreases stretch-activated contractility in airway smooth muscle tissue ex vivo and inhibits OVA-induced bronchoconstriction in vivo.…
Memantine Hydrochloride Memantine is an inhibitor of NMDA receptors that exhibits neuroprotective and cognition enhancing activities and is clinically used to treat Alzheimer’s disease, dementia, and Parkinson’s disease. Memantine also…
Melphalan Melphalan is a nitrogen mustard alkylator and a derivative of mechlorethamine. Melphalan exhibits anticancer chemotherapeutic activity, attaching alkyl groups to the N7 nitrogen of guanine bases on DNA, preventing…
Meloxicam Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2; it exhibits anti-inflammatory, analgesic, antipyretic, neuroprotective, antioxidative, and hepatoprotective activities. In animal models of Parkinson’s disease, meloxicam inhibits MPTP-induced…
Melittin Melittin is an antimicrobial peptide (AMP) found in Apis mellifera venom that exhibits antifungal, antibacterial, antiviral, and anti-parasitic activities. In Candida, melittin increases formation of radicals, decreases the mitochondrial…
Melitracen Hydrochloride Melitracen hydrochloride is an clinically acceptable effective tricyclic antidepressant that exerts no harmful cardiac side effects, unlike many other antidepressants. This compound is often administered with flupenthixol as…
Melatonin Melatonin is an endogenous hormone involved in circadian rhythms. Melatonin activates melatonin (MT) receptors and decreases expression of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and leptin; it exhibits sedative,…
Melanotan II Melanotan II is a synthetic melanocortin peptide analog that exhibits thermogenic, anti-inflammatory, and anti-atherosclerotic activities; it non-selectively binds melanocortin receptors. Melanotan II was originally designed to promote skin…
Melanostatin, frog Melanostatin is a neuromodulatory peptide of the MIF-1 family. Melanostatin modulates D2 receptor dopamine signaling and downstream effects. Additionally, this peptide potentiates antidepressant activity of amitriptyline and desipramine…