PHT-427
PHT-427 PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC). References…
2017
Phosphate Acceptor Peptide
Phosphate Acceptor Peptide Phosphate acceptor peptide is a substrate of PKC and S6 kinase. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18954071 Purity ≥95% Formula C41H74N16O11 Formula Wt. 967.15 Appearance White to off white powder…
Phorbol-12,13-dibutyrate
Phorbol-12,13-dibutyrate Phorbol 12,3-dibutyrate (PBDu) activates PKC and PKD and induces apoptosis and differentiation in leukemia cells. PBDu is carcinogenic. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18953766 Cas No. 37558-16-0 Purity ≥98% Formula C30H46O8 Formula…
Phorbol-12-myristate-13-acetate
Phorbol-12-myristate-13-acetate Phorbol-12-myristate-13-acetate (PMA) activates PKC and induces DNA damage. PMA exhibits pro-inflammatory, carcinogenic, and cytotoxic activities. This compound is often used in research models as a tumor promoter. References PubMed…
Phleomycin
Phleomycin Phleomycin is a glycopeptide antibiotic that binds DNA but does not intercalate. Phleomycin is mutagenic and requires metal ions to induce double-stranded DNA breaks. This compound displays some antibacterial…
Phenylhexyl Isothiocyanate
Phenylhexyl Isothiocyanate Isothiocyanates are compounds typically found in plants of the Brassicaceae family, including broccoli, cabbage, and radish. Isothiocyanates are best known for their antioxidative, anticancer chemotherapeutic, chemopreventive, anti-angiogenic, and…
Phenylethyl-4-methylcaffeate
Phenylethyl-4-methylcaffeate This compound is a derivative of methyl caffeate, a hydroxycinnamic acid; it exhibits chemopreventive potential, inhibiting the development of colon tumors in vivo. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18953600 Purity ≥98% Formula…
Phenylethyl 3-methylcaffeate
Phenylethyl 3-methylcaffeate Phenylethyl 3-methylcaffeate exhibits anticancer chemotherapeutic and chemopreventive activities. Phenylethyl-3-methylcaffeate is a hydroxycinnamic acid and derivative of methylcaffeate. This compound decreases the incidence, number, and volume of tumors in…
Phenylbutyrate Sodium
Phenylbutyrate Sodium Phenylbutyrate is an inhibitor of histone deacetylase (HDAC) that exhibits neuroprotective and anticancer chemotherapeutic activities. In cellular and animal models of pancreatic cancer, phenylbutyrate inhibits cellular proliferation and…
Phenylbutazone
Phenylbutazone Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 activity; it is no longer used in humans, but was previously used to treat inflammatory diseases such…