Ramatroban Ramatroban is a thromboxane A2 (TxA2) receptor inhibitor that exhibits anti-allergic and anti-inflammatory properties. Ramatroban also competitively inhibits chemoattractant receptor-homologous molecule on Th2 cells (CRTH2), a relatively new prostaglandin…
Raltitrexed Raltitrexed is a quinazoline analog of folate. Raltitrexed acts as an antifolate anticancer chemotherapeutic, inhibiting thymidylate synthase. Raltitrexed disrupts DNA synthesis and induces strand breaks. This compound is approved…
Raltegravir Raltegravir is an antiviral compound that inhibits HIV integrase; it is clinically used to treat HIV infection. In pre-clinical models, raltegravir decreases infection rates by preventing insertion of HIV-1…
Raloxifene Hydrochloride Raloxifene is a selective estrogen receptor modulator (SERM) that exhibits agonist activity in bone and antagonist activity in uterine and breast tissues. Raloxifene is clinically used to prevent…
RAF265 RAF265 is an orally bioavailable anticancer chemotherapeutic compound that inhibits primarily WT B-Raf, mutant (V600E) B-Raf, and VEGFR2, but is also active against c-Raf, PDGFR, CSF-1R, RET, c-Kit, Src,…
Radicicol Radicicol is an analog of benzoquinone ansamycin that inhibits HSP90, Src family kinases, and Raf. Radicicol exhibits neuroprotective, antibiotic, antifungal, anti-parasitic, and antimalarial activities. In Plasmodium, radicicol targets topoisomerase…
Ractopamine Hydrochloride Ractopamine is an agonist at β1/2-adrenergic receptors that is used in livestock to increase muscle mass and decrease body fat. In vivo, administration of ractopamine decreases retroperitoneal and…
Racecadotril Racecadotril is an inhibitor of enkephalinase that prevents degradation of endogenous opioids and decreases secretion of water and electrolytes in the intestines. Racecadotril exhibits anti-secretory and antidiarrheal activities and…
Rabeprazole Sodium Rabeprazole is a proton pump inhibitor (PPI) that exhibits antacid activity, as it is clinically used to treat gastric ulcers and gastroesophageal reflux disease (GERD). Rabeprazole binds cysteine…
R,S-Sulforaphane, Research Grade R,S-Sulforaphane is a synthetic isothiocyanate. R-Sulforaphane is the naturally-occurring isomer, found in broccoli. This compound exhibits antioxidative, neuroprotective, anti-inflammatory, anti-atherosclerotic, neuromodulatory, cardioprotective, anticoagulant, antibiotic, anticancer chemotherapeutic, and…