Roxatidine Acetate Hydrochloride Roxatidine is an antihistamine compound that inhibits H2 histamine receptors, exhibiting antacid and anti-ulcerative activities by preventing gastric acid secretion. Roxatidine also inhibits indomethacin-induced small intestinal injury…
Rotenone Rotenone is a pesticide that exhibits genotoxic, pro-oxidative, and neurodegenerative properties. In vitro, rotenone induces formation of micronuclei and modifies the microtubule organizing centers of mitotic spindles. In other…
Rosuvastatin Calcium Rosuvastatin is an inhibitor of HMG-CoA reductase that decreases serum LDL and VLDL and is used to treat atherosclerosis in clinical settings. In addition to anti-atherosclerotic benefit, rosuvastatin…
Rosmarinic Acid Rosemarinic acid is a caffeic acid ester found in many plants, including Melissa, Salvia, Ocimum, Rosmarinus, and Origanum. Rosemarinic acid exhibits antidepressant, neuroprotective, anti-inflammatory, anti-allergic, anti-angiogenic, anti-fibrotic, and…
Rosiglitazone Maleate Rosiglitazone is a thiazolidinedione insulin sensitizer that activates PPARγ, decreasing blood glucose and insulin levels. Rosiglitazone exhibits anti-diabetic, anti-inflammatory, antioxidative, anticancer, anti-angiogenic, antihypertensive, and anti-fibrotic activities. In vivo,…
Rosiglitazone Rosiglitazone is a thiazolidinedione insulin sensitizer that activates PPARγ, decreasing blood glucose and insulin levels. Rosiglitazone exhibits anti-diabetic, anti-inflammatory, antioxidative, anticancer, anti-angiogenic, antihypertensive, and anti-fibrotic activities. In vivo, rosiglitazone…
Roscovitine Roscovitine is an inhibitor of CDKs (1, 2, 5, 7, 9, 12) and L-type Ca2+ channels; it exhibits anti-inflammatory and anticancer activities. Roscovitine resolves neutrophil-driven inflammation. In B-cell lymphoma…
Ropinirole Hydrochloride Ropinirole is an indoline agonist at D2/3 receptors that is clinically used to treat restless leg syndrome and Parkinson’s disease. Ropinirole prevents dopaminergic neuron damage and MPTP-induced changes…
Romidepsin Romidepsin is a depsipeptide prodrug that inhibits histone deacetylases (HDACs). Romidepsin is currently in clinical trials as a potential treatment for T-cell lymphomas; it displays anticancer chemotherapeutic and antiviral…
Rolipram Rolipram is known to be an antidepressant and anxiolytic-like agent that has been found to stimulate angiogenesis and attentuate neuronal apoptosis in ischemic rats. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18964309 Cas No.…