Scriptaid
Scriptaid Scriptaid is an inhibitor of histone deacetylases that exhibits anticancer activity. In non-small cell lung cancer (NSCLC) cells, scriptaid downregulates expression of Chk1. In glioma cells, scriptaid increases activation…
2017
Scopolamine N-butylbromide
Scopolamine N-butylbromide Scopolamine is a tropane alkaloid found in Solanaceae family plants that exhibits antiemetic and anticholinergic activities. Scopolamine inhibits muscarinic acetylcholine receptors (mAChRs) with a moderate selectivity for M1…
Scopolamine Hydrobromide Trihydrate
Scopolamine Hydrobromide Trihydrate Scopolamine is a tropane alkaloid found in Solanaceae family plants that exhibits antiemetic and anticholinergic activities. Scopolamine inhibits muscarinic acetylcholine receptors (mAChRs) with a moderate selectivity for…
Schisantherin A
Schisantherin A Schisantherin A is a dibenzocyclooctadiene originally found in Schisandra that exhibits anti-tussive, sedative, anti-inflammatory, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. In macrophages, schisantherin A decreases LPS-induced expression…
SB-431542
SB-431542 SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7; this inhibition leads to inhibition of activin and TGF-β signaling with no downstream effects on ERK, JNK, or MAPK. SB-431542…
Satraplatin
Satraplatin Satraplatin is a platinum-based anticancer chemotherapeutic that is used in cisplatin-resistant cancers; like other platinum compounds, it forms DNA adducts and inhibits DNA repair. Satraplatin induces G2/M phase cell…
Sarcophine
Sarcophine Sarcophine is a marine cembranoid diterpene found in the Red Sea soft coral Sarcophyton glaucum. Sarcophine and its synthetic derivative, sarcophine-diol, exhibit chemopreventive activity. In vivo, sarcophine inhibits skin…
Sarafotoxin 6c
Sarafotoxin 6c Sarafotoxin 6C (S6C) is an isoform of a toxin found in the venom of Atractaspis engaddensis snakes. S6C acts as a peptide agonist at endothelin B (ET-B) receptors…
Sarafloxacin Hydrochloride
Sarafloxacin Hydrochloride Sarafloxacin is a fluoroquinolone antibiotic that inhibits topoisomerase IV and DNA gyrase. Sarafloxacin displays antibacterial activity against Mycobacterium, Escherichia, and several other bacteria. This compound is most often…
Saikosaponin C
Saikosaponin C Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities. In vitro, saikosaponin C increases cell growth, cell migration, and capillary tube formation.…