Hexarelin Hexarelin is a synthetic analog of ghrelin that binds and activates the ghrelin (GHS) receptor. Hexarelin exhibits cardioprotective, anti-fibrotic, antihypertensive, and anti-fertility activities. In animal models of myocardial infarction,…
Hexamethylene Bisacetamide Hexamethylene bisacetamide (HMBA) activates hexamethylene bisacetamide-inducible protein 1 (HEXIM1), inhibiting transcription elongation factor b (P-TEFb), a regulator of RNA polymerase II and mRNA synthesis. HMBA exhibits anticancer activity…
Hexamethonium Bromide Hydrate Hexamethonium bromide is a non-depolarizing neuromuscular junction (NMJ) blocker that acts as an antagonist at pre-ganglionic nicotinic acetylcholine receptors (nAChRs). Hexamethonium bromide was previously used to treat…
Hexaconazole Hexaconazole is a triazole antifungal pesticide; it acts as a demethylation inhibitor, preventing sterol biosynthesis and disrupting membrane function. Hexaconazole may also display other activities, as it induces production…
Hesperidin Hesperidin is a phytoestrogen and flavonoid found in citrus plants that exhibits anti-hyperlipidemic, anti-osteoporotic, anti-inflammatory, analgesic, sedative, antinociceptive, and antioxidative activities. In vivo, hesperidin increases levels of HDL and…
Hesperetin Hesperetin is a phytoestrogen and flavanone found in citrus plants that exhibits analgesic, antinociceptive, anti-inflammatory, antioxidative, cardioprotective, anti-fibrotic, anticancer, and anti-metastatic activities. Hesperetin inhibits mechanical and thermal hyperalgesia and…
Herbimycin A Herbimycin A is a benzoquinone ansamycin antibiotic that also exhibits anticancer activity. Herbimycin A inhibits HSP90, PKC, and some Src family kinases such as Src and Bcr-Abl. Herbimycin…
HER2/neu Fragment (869-877) HER2/neu (869-877) is a peptide fragment of the HER2/neu receptor, also known as CD340, EGFR2, or erbB2. This receptor exhibits anti-apoptotic activity and is associated with breast…
HER2/neu (654-662) GP2 HER2/neu (654-662) is a peptide fragment of the HER2/neu receptor, also known as CD340, EGFR2, or erbB2. This receptor exhibits anti-apoptotic activity and is associated with breast…
Heptaplatin Heptaplatin is a platinum-complexed anticancer chemotherapeutic compound approved in some countries for the treatment of gastric cancers. Heptaplatin exhibits anti-proliferative activity in models of head and neck squamous cell…