Methysticin Methysticin is a kavalactone originally found in Piper methysticum (kava plant). Methysticin exhibits neuroprotective, neuromodulatory, and antifungal activities. Methysticin may also display anti-inflammatory benefit, inhibiting activation of NF-κB in…
Methylprednisolone Methylprednisolone is a synthetic glucocorticoid that displays anti-inflammatory and immunosuppressive activities. In vitro, methylprednisolone decreases survival of activated CD4+ T cells. In glioblastoma cells, this compound inhibits oxidative stress-induced…
Methyldopa Sesquihydrate Methyldopa exhibits antihypertensive and sedative activities. In circulation, methyldopa is metabolized to α-methylnorepinephrine by dopamine β-hydroxylase, which activates α2-adrenergic receptors, acting as a sympatholytic and inhibiting the sympathetic…
Methyl Salicylate Methyl salicylate can be found in Spiraea, Betula, and Gaultheria; it exhibits analgesic activity. Methyl salicylate is commercially used as an antiseptic, a wintergreen flavorant/tastant, and as a…
Methyl Caffeate Methyl caffeate is a polyphenol found in species of Solanum and Magnolia; it exhibits antibiotic, anti-diabetic, antiviral, and anticoagulant activities. Methyl caffeate displays antibacterial efficacy against Pseudomonas, Klebsiella,…
Methoxy Ferintoic Acid A Methoxy ferintoic acid A is a hexapeptide found in Microcystis; its biological activity is unknown. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18944380 Purity ≥95% Formula C47H60N8O9 Formula Wt. 881.03 Williams…
Methotrexate Hydrate Methotrexate is an antimetabolite that exhibits immunosuppressive, abortifacient, anti-inflammatory, and anticancer chemotherapeutic activities. Methotrexate is clinically used to treat various cancers, ectopic pregnancy, and rheumatoid arthritis. Methotrexate inhibits…
Methimazole Methimazole is a thioamide immunomodulatory anti-thyroid compound that is clinically used to treat hyperthyroidism and Graves’ disease. Methimazole is an irreversible inhibitor of thyroid peroxidase; it decreases levels of…
Methazolamide Methazolamide is a carbonic anhydrase inhibitor that exhibits anti-glaucoma and anti-diabetic activities. Methazolamide decreases blood glucose and Hb1(Ac) levels and improves glucose tolerance. This compound is clinically used to…
Metformin Hydrochloride Metformin is an AMPK activator that exhibits anti-diabetic, antihyperglycemic, antioxidative, immunosuppressive, anticancer chemotherapeutic, anti-metastatic, and chemopreventive activities. Metformin modulates glucose-6-phosphatase activity, decreasing glucose production and glycogenolysis. Additionally, it…