Olopatadine Hydrochloride Olopatadine hydrochloride is an antihistamine clinically used to treat allergic rhinitis and allergic conjunctivitis. This compound acts as a mast cell stabilizer, preventing histamine and TNF-α release from…
Olomoucine Olomoucine is a purine derivative that inhibits CDKs and exhibits anti-inflammatory, neuroprotective, and anticancer activities. In macrophages, olomoucine decreases levels of NO and iNOS and suppresses activation of NF-κB.…
Olmesartan Medoxomil Olmesartan medoxomil is an angiotensin II type 1 receptor (AT1) inhibitor that inhibits negative regulatory feedback on renin secretion, decreasing secretion of aldosterone and resulting in decreased peripheral…
Oligomycin A Oligomycin A is a macrolide antibiotic initially produced by several species of Streptomyces. Oligomycin A inhibits mitochondrial F1F0 ATP synthase, binding the F0 subunit, inhibiting ATP synthesis. Oligomycin…
Oligomycin This product consists of a mixture of oligomycins A, B and C. Oligomycins are macrolide antibiotics that exhibit antibacterial activity. Oligomycins suppress oxidative phosphorylation in the mitochondria by inhibiting…
Oleanolic Acid Oleanolic acid is a triterpenoid originally found in Vigna angularis and Trigonella foenum-graecum. Oleanolic acid exhibits anticancer, anti-inflammatory, anti-allergic, anti-resorptive, and anti-osteoporotic activities. In hypertrophic scar fibroblasts, oleanolic…
Olaparib Olaparib is an inhibitor of poly(ADP-ribose) polymerase (PARP 1/2) that prevents DNA repair. Olaparib displays benefit in clinical trials of BRCA mutation-harboring ovarian and breast cancers as well as…
Olanzapine Olanzapine is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, panic disorder, anxiety, and Tourette’s syndrome. Olanzapine acts as an antagonist or inverse agonist at D1-4 receptors, 5-HT1A/2/3/6/7…
Okadaic Acid Sodium Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and…
Okadaic Acid Ammonium Okadaic acid is a diarrhetic shellfish toxin initially produced by dinoflagellates and sea sponges; it exhibits neurotoxic and anticancer activities. Okadaic acid inhibits protein phosphatases 1 and…