OTX-015
OTX-015 OTX-015 is an inhibitor of bromodomains (BRD) proteins such as BRD2/3/4; it is currently in clinical trials as a potential treatment for leukemias and other cancers. OTX-015 displays anticancer…
June 2017
Osthole
Osthole Osthole is an O-methylated coumarin that inhibits Ca2+ channels. It exhibits anticancer, antioxidative, anti-inflammatory, and cardioprotective activities. In glioblastoma cells, osthole inhibits IGF-1-induced epithelial-to-mesenchymal transition (EMT), decreases phosphorylation of…
OSI-906
OSI-906 OSI-906 inhibits IGF-1R and InsR, displaying anticancer chemotherapeutic activity; it is currently in clinical trials as a potential treatment for colorectal cancer. In animal models of ovarian cancer, OSI-906…
OSI-027
OSI-027 OSI-027 is an inhibitor of mTORC1/2 that exhibits anticancer chemotherapeutic activity. In vitro, OSI0027 inhibits phosphorylation of downstream target Akt, inhibiting cell proliferation in breast cancer cells. OSI-027 also…
Oseltamivir Phosphate
Oseltamivir Phosphate Oseltamivir is an antiviral compound that is used clinically to treat influenza infection. Oseltamivir covalently inhibits viral neuraminidase. This compound may also inhibit monoamine oxidase A (MAO-A), increasing…
Oscillamide Y
Oscillamide Y Oscillamide Y is a cyanotoxin found in species of the cyanobacterium Planktothrix (Oscillatoria). Oscillamide Y is a ureido-containing cyclic peptide that inhibits protein phosphatases such as PP1 and…
Oscillaginin C
Oscillaginin C Oscillaginins are linear peptides found in cyanobacteria such as Oscillatoria agardhii. Like other cyanotoxins, oscillaginins likely inhibit protein phosphatases (PPs). References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18951280 Purity ≥95% Formula C29H46Cl2N4O8 Formula…
Oscillaginin B Methyl Ester
Oscillaginin B Methyl Ester Oscillaginins are linear peptides found in cyanobacteria such as Oscillatoria agardhii. Like other cyanotoxins, oscillaginins likely inhibit protein phosphatases (PPs). References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1895124 Purity ≥95% Formula…
Oscillaginin B
Oscillaginin B Oscillaginins are linear peptides found in cyanobacteria such as Oscillatoria agardhii. Like other cyanotoxins, oscillaginins likely inhibit protein phosphatases (PPs). References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18951186 Cas No. 189438-21-9 Purity ≥95%…
Oscillaginin A Methyl Ester
Oscillaginin A Methyl Ester Oscillaginins are linear peptides found in cyanobacteria such as Oscillatoria agardhii. Like other cyanotoxins, oscillaginins likely inhibit protein phosphatases (PPs). References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18951090 Purity ≥95% Formula…