Tuftsin
Tuftsin Tuftsin is a tetrapeptide that binds the neuropilin-1 (Nrp1) receptor, modulating TGF-β, cGMP, and Ca2+ signaling. Tuftsin is derived from the Fc region of IgG. Tuftsin exhibits immunomodulatory activity,…
June 2017
Tubeimoside I
Tubeimoside I Tubeimoside I is a triterpene saponin originally found in Bolbostemma that exhibits anti-inflammatory, antiviral, anticancer chemotherapeutic, and chemopreventive activities. Tubeimoside I inhibits LPS-stimulated production of TNF-α, IL-1β, and…
Troglitazone
Troglitazone Troglitazone is a thiazolidinedione PPARγ agonist that exhibits anti-diabetic, anticancer, anti-fibrotic, and anti-inflammatory activities. Troglitazone contains a vitamin E-like ring structure that forms hepatotoxic metabolites in vivo. Troglitazone induces…
Triticonazole
Triticonazole Triticonazole is a triazole pesticide/fungicide with broad antifungal activity. Like many azole fungicides, triticonazole likely inhibits 14-α demethylase, inhibiting ergosterol production and fungal cell wall synthesis. Additionally, triticonazole may…
Triptorelin Acetate
Triptorelin Acetate Triptorelin is an analog of gonadotropin-releasing hormone I (GnRH-I); it is a decapeptide that activates the GnRH receptor in the pituitary gland, decreasing secretion of luteinizing hormone (LH)…
Triptorelin
Triptorelin Triptorelin is a peptide analog of gonadotropin-releasing hormone (GnRH) that induces constant stimulation of the pituitary gland, decreasing release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Triptorelin exhibits…
Triptolide
Triptolide Triptolide is a diterpenoid epoxide originally found in Tripterygium that exhibits anticancer chemotherapeutic, anti-angiogenic, antinociceptive, anti-inflammatory, anti-fibrotic, and immunosuppressive activities. Triptolide induces apoptosis and decreases β-catenin expression in breast…
Trimethoprim
Trimethoprim Trimethoprim is an antibiotic that inhibits dihydrofolate reductase, acting as an anti-folate. Trimethoprim exhibits antibacterial activity against both gram positive and gram negative bacteria and is clinically used to…
Trimetazidine
Trimetazidine Trimetazidine is a compound that exhibits anti-anginal, anti-ischemic, and cardioprotective activities; it inhibits long-chain 3-ketoacyl-CoA thiolase. Trimetazidine reverses pro-inflammatory effects of TNF-α in animal models, including preventing decreases in…
Trimebutine Maleate
Trimebutine Maleate Trimebutine exhibits antibacterial and gastrointestinal motility modulating activities; it is clinically used to treat irritable bowel syndrome (IBS). Trimebutine displays antibiotic activity against Escherichia and Pseudomonas. This compound…