5-Bromo-2′-Deoxyuridine
5-Bromo-2′-Deoxyuridine 5-Bromo-2’-deoxyuridine is a synthetic nucleoside analog of thymidine that is used in research models to label actively proliferating cells. This compound is incorporated into DNA but at low levels…
June 2017
5-Aza-2′-deoxycytidine
5-Aza-2′-deoxycytidine Decitabine is a deoxycytidine analog that is incorporated into DNA, inhibiting DNA methyltransferase (DNMT1/3A/3B) activity. This demethylating agent is clinically used to treat myelodysplastic syndromes. Decitabine’s inhibition of DNA…
5-(9-Isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
5-(9-Isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine This compound Is an intermediate in the synthesis of purine analogs and potential tyrosine kinase inhibitors. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834327 Cas No. 1246535-95-4 Purity ≥98% Formula C16H20N8O Formula Wt. 340.39…
4′-Demethylepipodophyllotoxin
4′-Demethylepipodophyllotoxin 4’-Demethylepipodophyllotoxin is a topoisomerase II inhibitor found in Podophyllum. Derivatives of this compound exhibit anticancer chemotherapeutic activity. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834323 Cas No. 6559-91-7 Purity ≥98% Formula C21H20O8 Formula Wt.…
4,4′-(1,1′-Biphenyl-4,4′-diyldioxy)dianiline
4,4′-(1,1′-Biphenyl-4,4′-diyldioxy)dianiline This compound may exhibit anti-angiogenic and anticancer benefit through the potential inhibition of VEGFR2 (Flk-1), Met, RET, Axl, Ron, PDGFR, FGFR1 (Flg), and FMS-related tyrosine kinases 1, 3, and…
4-α-Phorbol-12-myristate-13-acetate
4-α-Phorbol-12-myristate-13-acetate 4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834305 Cas No. 63597-44-4…
4-Thiouridine
4-Thiouridine 4-Thiouridine is a modified nucleotide that induces DNA cross-linking after irradiation with UV light. This compound is often used for labeling DNA in research models. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834282 Cas…
4-tert-Butyl-5-Methoxycatechol
4-tert-Butyl-5-Methoxycatechol 4-Tert-butyl-5-methoxy-catechol exhibits anticancer activity, inhibiting proliferation of leukemia cells. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834263 Cas No. 91352-66-8 Purity ≥98% Formula C11H16O3 Formula Wt. 196.25 IUPAC Name 4-tert-butyl-5-methoxybenzene-1,2-diol Melting Point 89-90°C Solubility…
4-tert-Butyl-5-Methoxy-1,2-quinone
4-tert-Butyl-5-Methoxy-1,2-quinone 4-Tert-butyl-5-methoxy-1,2-quinone exhibits anticancer activity, inhibiting proliferation of leukemia cells. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834225 Cas No. 36122-03-9 Purity ≥98% Formula C11H14O3 Formula Wt. 194.25 IUPAC Name 4-tert-butyl-5-methoxycyclohexa-3,5-diene-1,2-dione Melting Point 92-95°C Appearance…
4-Phenylbutylisothiocyanate
4-Phenylbutylisothiocyanate 4-Phenylbutyl isothiocyanate (ITC) is a synthetic ITC that exhibits anticancer chemotherapeutic and chemopreventive activities. In vitro, this compound induces caspase 3-dependent apoptosis. 4-Phenylbutyl isothiocyanate inhibits the development of pancreatic…