Amsacrine
Amsacrine Amsacrine is an anticancer chemotherapeutic acridine derivative that is clinically used to treat acute myelogenous leukemia (AML). Amsacrine acts as a DNA intercalator, binding AT base pairs; this inhibits…
June 2017
Amrinone
Amrinone Amrinone is a pyridine phosphodiesterase 3 (PDE 3) inhibitor that is clinically used to treat congestive heart failure (CHF). Amrinone may be administered during cardiopulmonary bypass surgery. Amrinone exhibits…
Amprolium Hydrochloride
Amprolium Hydrochloride Amprolium is an anti-parasitic coccidiostat used in veterinary medicine. Amprolium is a thiamine analog that inhibits thiamine transporters in species of Eimeria, preventing carbohydrate synthesis. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18838414…
Ampiroxicam
Ampiroxicam Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities; it inhibits COX-1 and COX-2. Ampiroxicam is a prodrug of piroxicam that does not inhibit prostaglandin…
Ampicillin Trihydrate
Ampicillin Trihydrate Ampicillin is a β-lactam antibiotic that displays antibacterial efficacy against both gram negative and gram positive bacteria. Ampicillin inhibits transpeptidase, preventing bacterial cell wall formation. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18838411…
Amphotericin B
Amphotericin B Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates…
Ampalex
Ampalex Ampalex is a benzylpiperidine AMPA receptor potentiator. It exhibits antipsychotic activity and may also show cognition enhancing and neuroprotective benefits. Ampalex modulates fast synaptic plasticity and memory process in…
Amoxicillin
Amoxicillin Amoxicillin is a β-lactam penicillin antibiotic that exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Amoxicillin inhibits peptidoglycan polymerization through binding of penicillin binding proteins, inhibiting…
Amoxapine
Amoxapine Amoxapine is a tricyclic antidepressant that acts as an antagonist at 5-HT2/3/6/7 receptors, D2/3/4 receptors, H1 histamine receptors, α1-adrenergic receptors, and also on the serotonin transporter (SERT) and norepinephrine…
Amorolfine Hydrochloride
Amorolfine Hydrochloride Amorolfine is an antifungal compound that prevents ergosterol synthesis through the inhibition of sterol 14α-demethylase. Amorolfine increases release of prostaglandin D2 metabolites, inhibiting release of thromboxane B2 (TxB2),…