Biapenem Biapenem is a carbapenem β-lactam antibiotic. Like other carbapenems, biapenem binds penicillin-binding proteins to inhibit bacterial cell wall synthesis. Biapenem exhibits broad spectrum antibacterial activity and is clinically used…
BI-6727 BI-6727 is a polo-like kinase 1 (PLK1) inhibitor that exhibits anticancer activity. In vitro, BI-6727 induces apoptosis in acute myelogenous leukemia (AML) cells. This compound is currently in clinical…
BI-2536 BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells. References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18843938 Cas…
Bezafibrate Bezafibrate is a PPARα agonist that is clinically used to lower LDL and triglyceride levels and to increase HDL levels. Bezafibrate exhibits anti-hyperlipidemic, cardioprotective, anti-diabetic, anti-osteoporotic, and anticancer chemotherapeutic…
BEZ235 BEZ235 inhibits PI3K and mTORC1/2, exhibiting anticancer chemotherapeutic activity. In nasopharyngeal cancer cells, BEZ235 induces G1 phase cell cycle arrest and apoptosis; in similar animal models of nasopharyngeal or…
Bexarotene Bexarotene is a retinoid compound that binds and activates retinoid X receptors (RXRs) and is approved to treat cutaneous T cell lymphoma. Bexarotene displays a wide variety of beneficial…
Betulinic Acid Betulinic acid is a pentacyclic triterpene that exhibits antithrombotic, anti-atherosclerotic, antioxidative, anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic properties. Betulinic acid decreases expression of P-selectin and binding of PAC-1, preventing…
Betulin-3-Acetate Betulin-3-acetate is a pentacyclic triterpene. This compound exhibits antiviral activity and anticancer potential. Betulin-3-acetate is a close relative of betulin, which has anticancer, antiviral, anti-inflammatory, and antibacterial activity. It…
Betulin Betulin is a pentacyclic triterpene found in birch bark. This compound can induce apoptosis and inhibit angiogenesis, lending it a wide variety of functions, including anticancer, antiviral, anti-inflammatory, anti-fibrotic,…
Betamethasone Valerate Betamethasone valerate (BMV) is a synthetic glucocorticoid that is commonly used to treat psoriasis and dermatitis. BMV exhibits immunomodulatory, anti-inflammatory, and vasoconstrictive activity in vitro and in vivo.…