Clonidine Hydrochloride Clonidine is an α2-adrenergic receptor agonist that also activate the imidazoline 1 receptor, increasing downstream catecholamine synthesis. Clonidine exhibits antihypertensive, neuromoduatory, cognition enhancing, antinociceptive, analgesic, and antipsychotic activities.…
Clomipramine Hydrochloride Clomipramine hydrochloride displays antidepressant and anxiolytic activity and may also be used to treat narcolepsy and obsessive-compulsive disorder (OCD). This compound inhibits serotonin transporters (SERT), norepinephrine transporters (NET),…
Clomiphene Citrate Clomiphene is a selective estrogen receptor modulator (SERM) that induces ovulation and is used clinically in assisted reproduction. Clomiphene inhibits estrogen receptors in the hypothalamus, upregulating release of…
Clofibric Acid Clofibric acid is a metabolite of clofibrate that activates PPARα receptors and inhibits auxin activity, exhibiting anti-hyperlipidemic, anti-angiogenic, anticancer chemotherapeutic, and herbicidal activity. Clofibric acid alters plant hormone…
Clofibrate Clofibrate is a fibrate compound that exhibits anti-hyperlipidemic and anticancer activities. Clofibrate acts as an agonist at PPARα, increasing lipoprotein lipase and HDL and decreasing triglycerides and VLDL. In…
Clofarabine Clofarabine is a second-generation nucleoside analog of adenosine. Clofarabine inhibits DNA polymerase and ribonucleotide reductase through binding in the A-site, preventing DNA synthesis. Clofarabine is clinically used to treat…
Clodronate Disodium Tetrahydrate Clodronate is a first-generation non-nitrogen-containing bisphosphonate that is used clinically for its anti-resorptive activity. Clodronate generates formation of a non-hydrolysable β-γ ATP analog that inhibits mitochondrial ADP/ATP…
Clobetasol Propionate Clobetasol is a corticosteroid that activates glucocorticoid receptors and exhibits anti-inflammatory and immunosuppressive activities. Clobetasol is clinically used to treat eczema, psoriasis, contact dermatitis, and several autoimmune diseases.…
Clindamycin Phosphate Clindamycin is a lincosamide antibiotic that exhibits antibacterial, anti-protozoan, anti-parasitic, and antimalarial activities. Clindamycin displays efficacy against anaerobic gram negative bacteria, Streptococcus, and Staphylococcus (particularly MRSA). Clindamycin binds…
Clindamycin Palmitate Hydrochloride Clindamycin is a lincosamide antibiotic that exhibits antibacterial, anti-protozoan, anti-parasitic, and antimalarial activities. Clindamycin displays efficacy against anaerobic gram negative bacteria, Streptococcus, and Staphylococcus (particularly MRSA). Clindamycin…