Citalopram Hydrobromide Citalopram is a selective serotonin reuptake inhibitor (SSRI) that inhibits the serotonin transporter (SERT); citalopram is clinically used for its antidepressant and anxiolytic activities, although it may prolong…
Cisplatin Cisplatin is a platinum-based cross-linking agent that exhibits anticancer chemotherapeutic activity. Cisplatin induces crosslinks between guanine bases on DNA; it is clinically used to treat various forms of cancer.…
Cisatracurium Besylate Cisatracurium is a non-depolarizing neuromuscular junction (NMJ) blocker; it binds the α-δ interface of postsynaptic nicotinic acetylcholine receptors (nAChRs). Cisatracurium acts as a skeletal muscle relaxant and is…
Ciprofloxacin Hydrochloride Monohydrate Ciprofloxacin is a second generation fluoroquinolone antibiotic that exhibits antibacterial activity against both gram negative and gram positive bacteria. Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, preventing…
Ciprofloxacin Ciprofloxacin is a second generation fluoroquinolone antibiotic that exhibits antibacterial activity against both gram negative and gram positive bacteria. Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA replication.…
Ciprofibrate Ciprofibrate is a PPARα agonist that exhibits anti-hyperlipidemic activity. Clinically, ciprofibrate decreases levels of triglycerides and total cholesterol and increases levels of HDL. In hepatoma cells, ciprofibrate increases NF-κB…
Cinnarizine Cinnarizine is an inhibitor of L-type voltage-gated Ca2+ channels that is clinically used to treat migraine and vertigo. Cinnarizine exhibits anticonvulsant/antiepileptic activity in combination with other therapies in animal…
Cinacalcet Hydrochloride Cinacalcet is an agonist at Ca2+-sensing receptors that is clinically used to treat secondary hyperparathyroidism with chronic kidney disease. Cinacalcet also displays anti-fibrotic activity. This compound decreases levels…
Cimetidine Cimetidine is an antihistamine that inhibits H2 histamine receptors, exhibiting antacid and anticancer chemotherapeutic activities. Cimetidine inhibits catalase activity and also acts as an antagonist at androgen receptors. Cimetidine…
Cilnidipine Cilnidipine is a dihydropyridine that exhibits antihypertensive, vasodilatory, antinociceptive, and nephroprotective activities. Cilnidipine acts as an antagonist at L-type and N-type voltage-gated Ca2+ channels. In subjects with hypertension, cilnidipine…