Cyclopiazonic Acid Cyclopiazonic acid is an inhibitor of sarco/endoplasmic reticulum Ca2+/ATPase (SERCA) pumps, increasing intracellular Ca2+ levels and altering contractility in smooth muscle tissues. Additionally, this compound inhibits proliferation of…
Cyclophosphamide Monohydrate Cyclophosphamide is a nitrogen mustard that acts as an alkylator, adding alkyl groups to the N7 nitrogen of guanine bases; this inhibits DNA repair and replication. Cyclophosphamide exhibits…
Cyclopamine Cyclopamine is a steroidal jerveratrum alkaloid found in Veratrum that binds Smo, inhibiting hedgehog (Shh) signaling pathways. Cyclopamine exhibits anticancer activity, decreases expression of Gli2 and Bcl-2, inhibiting proliferation…
Cycloheximide Cycloheximide was initially produced by Streptomyces. Cycloheximide inhibits protein synthesis in eukaryotes by preventing tRNA translocation and elongation. Cycloheximide is not used in humans due to its high toxicity.…
Cyclocytidine Hydrochloride Cyclocytidine is a pyrimidine nucleoside analog that inhibits DNA synthesis; it exhibits antiviral and anticancer chemotherapeutic activities. Cyclocytidine induces degranulation of granular tubules in research models. This compound…
CYC-116 CYC-116 inhibits aurora kinases B and C (AurB, AurC), preventing mitotic spindle formation and proper completion of mitosis. This compound exhibits anticancer chemotherapeutic activity and is currently in clinical…
Cyanopeptolin 1068 MB Cyanopeptolins are cytotoxic serine protease inhibitors that was initially produced by species of cyanobacteria Microcystis. These peptides inhibit chymotrypsin, trypsin, plasmin, and elastase. Cyanopeptolins may also exhibit…
Cyanopeptolin 1054 MB2 Cyanopeptolins are cytotoxic serine protease inhibitors that was initially produced by species of cyanobacteria Microcystis. These peptides inhibit chymotrypsin, trypsin, plasmin, and elastase. Cyanopeptolins may also exhibit…
Cyanopeptolin 1054 MB1 Cyanopeptolins are cytotoxic serine protease inhibitors that was initially produced by species of cyanobacteria Microcystis. These peptides inhibit chymotrypsin, trypsin, plasmin, and elastase. Cyanopeptolins may also exhibit…
Cyanopeptolin 1041 Cyanopeptolins are cytotoxic serine protease inhibitors that was initially produced by species of cyanobacteria Microcystis. These peptides inhibit chymotrypsin, trypsin, plasmin, and elastase. Cyanopeptolins may also exhibit some…